Results 141 to 150 of about 37,551,526 (314)
Closure to “Hydrology of Spillway Design: Small Structures – Limited Data” [PDF]
Harold O. Ogrosky
openalex +1 more source
Separation logic: a logic for shared mutable data structures
J. C. Reynolds
semanticscholar +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Transactional Memory: Architectural Support For Lock-free Data Structures
Maurice Herlihy
semanticscholar +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
A high-level data manipulation language for hierarchical data structures [PDF]
Barron C. Housel, Nan C. Shu
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
ON SOME ENTERTAINING APPLICATIONS OF THE CONCEPT OF SET IN COMPUTER SCIENCE COURSE
Some aspects of programming education are examined in this work. It is emphasised, based on the entertainment value, the most appropriate examples are chosen to demonstrate the different language constructions and data structures.
K. Yordzhev, H. Kostadinova
doaj