Results 51 to 60 of about 2,861,627 (269)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
In this paper, a multiscale virtual particle based elastic network model (MVP-ENM) is proposed for the normal mode analysis of large-sized biomolecules.
Xia, Kelin
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Political Opportunity Structures - Parties
Data on the political opportunity structure (POS) in 7 Western European countries (Austria, Belgium, Ireland, Netherlands, Spain, Switzerland, and United Kingdom) between 1990 and 2009.
Joost Berkhout +9 more
core +1 more source
Segment-Based Clustering of Hyperspectral Images Using Tree-Based Data Partitioning Structures
Hyperspectral image classification has been increasingly used in the field of remote sensing. In this study, a new clustering framework for large-scale hyperspectral image (HSI) classification is proposed.
Mohamed Ismail, Milica Orlandić
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ethereum platform operates with rich spectrum of data structures and hashing and coding functions. The main source describing them is the Yellow paper, complemented by a lot of informal blogs. These sources are somehow limited. In particular, the Yellow paper does not ideally balance brevity and detail, in some parts it is very detail, while too ...
openaire +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Array-based Compact Data Structures for Triangulations: Practical Solutions with Theoretical Guarantees [PDF]
International audienceWe consider the problem of designing space efficient solutions for representing triangle meshes. Our main result is a new explicit data structure for compactly representing planar triangulations: if one is allowed to permute input ...
Devillers, Olivier +1 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

