Results 71 to 80 of about 37,551,526 (314)

A symbolic-arithmetic for teaching double-black node removal in red-black trees

open access: yesОсвітній вимір, 2022
A red-black (RB) tree is a data structure with red and black nodes coloration. The red and black color of nodes make up the principal component for balancing a RB tree. A balanced tree has an equal number of black nodes on any simple path.
Kennedy E. Ehimwenma   +3 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

A novel two‐stage method to detect non‐technical losses in smart grids

open access: yesIET Smart Cities
Numerous strategies have been proposed for the detection and prevention of non‐technical electricity losses due to fraudulent activities. Among these, machine learning algorithms and data‐driven techniques have gained prominence over traditional ...
Sufian A. Badawi   +10 more
doaj   +1 more source

Prospects and limitations of full-text index structures in genome analysis [PDF]

open access: yes, 2012
The combination of incessant advances in sequencing technology producing large amounts of data and innovative bioinformatics approaches, designed to cope with this data flood, has led to new interesting results in the life sciences.
Dawyndt, Peter   +3 more
core   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

THE STUDY OF THE INFLUENCE OF ASYMMETRY ON THE COMPLEXITY OF SOLVING THE TRAVELING SALESMAN PROBLEM BY THE BRANCH AND BOUND METHOD

open access: yesСовременные информационные технологии и IT-образование, 2019
The traveling salesman problem is the one of the most famous combinatorial optimization problems. This problem is important and at the same time difficult to solve, due to the exponential complexity of the exact methods of solution.
Nikolay V. Mamonov
doaj   +1 more source

Expanding the Scope of Statistical Computing: Training Statisticians to Be Software Engineers

open access: yesJournal of Statistics and Data Science Education, 2021
Traditionally, statistical computing courses have taught the syntax of a particular programming language or specific statistical computation methods.
Alex Reinhart, Christopher R. Genovese
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Efficient data structures for masks on 2D grids

open access: yes, 2015
This article discusses various methods of representing and manipulating arbitrary coverage information in two dimensions, with a focus on space- and time-efficiency when processing such coverages, storing them on disk, and transmitting them between ...
Hivon, Eric, Reinecke, Martin
core   +2 more sources

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