Results 71 to 80 of about 2,336,702 (258)

Review of Advanced Data Structures for Streaming Data Handling in Machine Learning Under Concept Drift

Proceedings of the International Conference on Applied Innovations in IT
Machine training on real-time flows introduces a significant hurdle, notably when a pattern change arises, a shift where data makeup or the link between input and output alters progressively.
Mithradevi Kumar, Aswathi KP, Janani Venugopal, Farah Ahmed Abdulrahman   +3 more
doaj   +1 more source

Data Structures for SMEM-Finding in the PBWT. [PDF]

Int Symp String Process Inf Retr, 2023
Bonizzoni P, Boucher C, Cozzi D, Gagie T, Köppl D, Rossi M.   +5 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Efficient Algorithms for Range Mode Queries in the Big Data Era

Information
The mode is a fundamental descriptive statistic in data analysis, signifying the most frequent element within a dataset. The range mode query (RMQ) problem expands upon this concept by preprocessing an array A containing n natural numbers.
Christos Karras, Leonidas Theodorakopoulos, Aristeidis Karras, George A. Krimpas   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Stable Structures for Distributed Applications [PDF]

Informatică economică, 2008
For distributed applications, we define the linear, tree and graph structure types with different variants and modalities to aggregate them. The distributed applications have assigned structures that through their characteristics influence the costs of ...
Eugen DUMITRASCU, Ion IVAN
doaj  

Hierarchical data structures for flowchart. [PDF]

Sci Rep, 2023
Zhang P, Dou W, Liu H.
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

fimpera: drastic improvement of Approximate Membership Query data-structures with counts. [PDF]

Bioinformatics, 2023
Robidou L, Peterlongo P.
europepmc   +1 more source