Results 61 to 70 of about 347,865 (289)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Array Structures and Data-Parallel Algorithms

open access: yes, 1996
. We integrate the semantics of higher-order functional programs with a notion of explicit static processes as used in BSP and PRAM algorithms. The result is the construction of a cartesian closed category (CCC), a model for typed functional languages.
John Mullins   +3 more
core   +1 more source

CS 3100: Data Structures and Algorithms [PDF]

open access: yes, 2013
Student learning outcomes include: Analyze basic algorithms for space and time complexity Design abstract data types appropriate for a given problem Implement data structures in an efficient manner Design and Implement non-graphical user-interfaces ...
Buck, Erik Marlow
core   +1 more source

A Linear Kernel for Planar Total Dominating Set [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2018
A total dominating set of a graph $G=(V,E)$ is a subset $D \subseteq V$ such that every vertex in $V$ is adjacent to some vertex in $D$. Finding a total dominating set of minimum size is NP-hard on planar graphs and W[2]-complete on general graphs when ...
Valentin Garnero, Ignasi Sau
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Experimental study of resilient algorithms and data structures

open access: yes, 2010
Large and inexpensive memory devices may suffer from faults, where some bits may arbitrarily flip and corrupt the values of the affected memory cells. The appearance of such faults may seriously compromise the correctness and performance of computations.
ITALIANO G   +11 more
core   +1 more source

Improved kernels for Signed Max Cut parameterized above lower bound on (r,l)-graphs [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2017
A graph $G$ is signed if each edge is assigned $+$ or $-$. A signed graph is balanced if there is a bipartition of its vertex set such that an edge has sign $-$ if and only if its endpoints are in different parts.
Luerbio Faria   +3 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Using Randomization in the Teaching of Data Structures and Algorithms

open access: yes, 1999
We describe an approach for incorporating randomization in the teaching of data structures and algorithms. The proofs we include are quite simple and can easily to Data Structures (CS2) course and a Junior-Senior level course on the design and analysis ...
Michael T. Goodrich, Roberto Tamassia
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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