Simulating time-to-event data subject to competing risks and clustering: A review and synthesis. [PDF]
Meng C +8 more
europepmc +1 more source
Chapter III of the GDPR provides for a set of rights that the data subjects can exercise to safeguard their personal data. This document discusses them in an accessible way.
Rigotti, Carlotta +3 more
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Data Protection in Zimbabwe with Reference to the Covid-19 Pandemic and International Law
The corona virus that caused the COVID-19 disease defied geographical boundaries, spreading faster than the measures to contain its transmission. The processing of personal health-related data became widespread as a measure to respond to the pandemic ...
Otto Saki
doaj +1 more source
Modeling unmeasured baseline information in observational time-to-event data subject to delayed study entry. [PDF]
Stegherr R +3 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Semiparametric copula method for semi-competing risks data subject to interval censoring and left truncation: Application to disability in elderly. [PDF]
Sun T, Li Y, Xiao Z, Ding Y, Wang X.
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Using natural language processing to study homelessness longitudinally with electronic health record data subject to irregular observations. [PDF]
Chapman AB +8 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

