Results 171 to 180 of about 27,692,945 (302)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Possibilidades e Limites da Anonimização de Dados Pessoais

Fronteiras da Representação do Conhecimento
According to the Brazilian General Data Protection Law ("LGPD"), anonymized data is not considered personal data. When data no longer allows the identification of the data subject, considering the use of reasonable and available technical means at the ...
Henrique Cunha Souza Lima, Gabriela Brasil Nascimento Almeida   +1 more
doaj  

Pandem-ethics: Post-mortem reflection on healthcare worker ethics during the time of coronavirus disease 2019 pandemonium. [PDF]

S Afr J Infect Dis
Bösenberg LH, Ueckermann V.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Grid development for energy justice and a just transition. [PDF]

iScience
Tormos-Aponte F.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Cultural participation rights as a proposed pathway for internal migrant mental health: an institutional analysis from China. [PDF]

Front Public Health
Zhang J, Li J.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Sports events as economic and political instruments: unpacking the dynamics of image creation through sport. [PDF]

Front Sports Act Living
Lejniece I, Kamenecka-Usova M, Židens J, Luika S, Korde Ž.   +4 more
europepmc   +1 more source

[Hitler, McCarthy, Anita - Act Now for Human Rights Poster]

Poster advertising the Breakfast Festival for Human Rights at Auditorium Shores. The poster features a black white and red graphic of Anita Bryant's head mid-speech. On the right is printed "Hitler - McCarthy - Anita".

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