Results 171 to 180 of about 546,186 (309)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Presence verification for summative e-assessments
, 2010 Influenced by information technology advances, the assessment process has begun to make its way out of the traditional classroom into online environments. Theonline summative assessment is a high-stake examination which counts towards a final course mark.
Apampa, Kikelomo Maria
core
Data Quality Assessment and Verification Methods
With the rapid growth of data volume, data quality has become increasingly critical. This study, based on literature review and practical experience in Taiwan, identifies 16 dimensions for multifaceted data quality evaluation. These include qualitative indicators, such as Currency, Comparability, Comprehensiveness, Relevance, Informed Consent ...
Wen-Chang Tseng +3 more
openaire +2 more sources
The Cooking and Pneumonia Study (CAPS) in Malawi: Implementation of Remote Source Data Verification. [PDF]
PLoS One, 2016 Weston W +3 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Performance Evaluation of zk-SNARK Protocols for Privacy-Preserving Sensor Data Verification: A Systematic Benchmarking Study. [PDF]
Sensors (Basel)Kuznetsov O +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Author Correction: Systematic data capture reduces the need for source data verification: exploratory analysis from a phase 2 multicenter randomized controlled platform trial. [PDF]
Commun Med (Lond)Abbasi AB +13 more
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source