Results 71 to 80 of about 1,559,860 (292)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Self-audits as alternatives to travel-audits for improving data quality in the Caribbean, Central and South America network for HIV epidemiology

open access: yesJournal of Clinical and Translational Science, 2020
Introduction:Audits play a critical role in maintaining the integrity of observational cohort data. While previous work has validated the audit process, sending trained auditors to sites (“travel-audits”) can be costly.
Sarah C. Lotspeich   +15 more
doaj   +1 more source

Data-Driven Digital Integrity Verification

open access: yes, 2022
AbstractImages and videos are by now a dominant part of the information flowing on the Internet and the preferred communication means for younger generations. Besides providing information, they elicit emotional responses, much stronger than text does.
Davide Cozzolino   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Algorithmic Verification of Asynchronous Programs

open access: yes, 2011
Asynchronous programming is a ubiquitous systems programming idiom to manage concurrent interactions with the environment. In this style, instead of waiting for time-consuming operations to complete, the programmer makes a non-blocking call to the ...
Abdulla P. A.   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A lifestyle-based prediction model for obesity in Chinese adolescent students

open access: yesFrontiers in Sports and Active Living
IntroductionAdolescent obesity has emerged as a critical global public health challenge, necessitating effective tools for early identification and intervention. This study aimed to identify significant contributing factors and develop a predictive model
Mei Jiang, Zhou He, Zhou He, Zhou He
doaj   +1 more source

Deep Learning Face Representation by Joint Identification-Verification [PDF]

open access: yes, 2014
The key challenge of face recognition is to develop effective feature representations for reducing intra-personal variations while enlarging inter-personal differences.
Sun, Yi, Tang, Xiaoou, Wang, Xiaogang
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Synthesizing Short-Circuiting Validation of Data Structure Invariants

open access: yes, 2015
This paper presents incremental verification-validation, a novel approach for checking rich data structure invariants expressed as separation logic assertions. Incremental verification-validation combines static verification of separation properties with
Chang, Bor-Yuh Evan   +3 more
core   +1 more source

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