Results 111 to 120 of about 1,372,066 (309)
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
In recent years, data-driven deep learning models have gained significant importance in the analysis of turbulent dynamical systems. Within the context of reduced-order models, convolutional autoencoders (CAEs) pose a universally applicable alternative ...
Philipp Teutsch+5 more
doaj +1 more source
Software for Quantitation and Visualization of Expression Array Data [PDF]
David Strehlow
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
MethTools--a toolbox to visualize and analyze DNA methylation data [PDF]
Christoph Grunau
openalex +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Color graphic data visualization system.
Ryoji Yanagi, Shigemi SHINDOU
openalex +2 more sources
A hierarchical error controlled octree data structure for large-scale visualization [PDF]
Dmitriy Pinskiy+5 more
openalex +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Visualization of scientific data - work performed for X-3. Final report
openalex +2 more sources