Results 81 to 90 of about 2,842,615 (341)

Hepamine - A Liver Disease Microarray Database, Visualization Platform and Data-Mining Resource [PDF]

open access: gold, 2020
Timo Itzel   +4 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Use of Remote Surface Based Tools for Visualizing Integrated Brain Imaging Data [PDF]

open access: yes, 2004
We describe a surface-based approach to 3D visualization of integrated neuroimaging data. Our web-enabled software allows researchers to use these visualization tools over the Internet.
Brinkley, James F   +2 more
core   +1 more source

Dynamical projections for the visualization of PDFSense data

open access: yes, 2018
A recent paper on visualizing the sensitivity of hadronic experiments to nucleon structure [1] introduces the tool PDFSense which defines measures to allow the user to judge the sensitivity of PDF fits to a given experiment.
Cook, Dianne   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Reinforcement Learning Algorithms and Applications in Healthcare and Robotics: A Comprehensive and Systematic Review

open access: yesSensors
Reinforcement learning (RL) has emerged as a dynamic and transformative paradigm in artificial intelligence, offering the promise of intelligent decision-making in complex and dynamic environments.
Mokhaled N. A. Al-Hamadani   +3 more
doaj   +1 more source

Surface Projection Method for Visualizing Volumetric Data [PDF]

open access: yes, 2006
The goal of this project was to explore, develop, and implement additional visualization methods for volumetric data within MindSeer. This paper discusses the implementation of one such visualization method, the surface projection method, and compares it
Lincoln, Peter
core   +1 more source

Data Comets: Designing a Visualization Tool for Analyzing Autonomous Aerial Vehicle Logs with Grounded Evaluation

open access: yes, 2020
Autonomous unmanned aerial vehicles are complex systems of hardware, software, and human input. Understanding this complexity is key to their development and operation.
Borkin, Michelle A.   +4 more
core   +1 more source

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