Results 81 to 90 of about 25,665,833 (303)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Interactive Hierarchical Data Investigation using Abstractions -- the Waltz Visualization Environment [PDF]

open access: yes, 1996
Scientific visualization is becoming common in the work-place; hastened by the growth in the power of computers generating data that needs to be visualized.
Roberts, Jonathan C.
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Visualization-Panel for Provenance Data [PDF]

open access: yes, 2008
Today’s IT-systems are becoming more difficult. Their relationship together grows as well as their complexity. Currently a main requirement is for people to trust more in the results and have a better understanding of the functionality.
Kunde, Markus
core  

Prolonged reduction in grassland arthropod activity after mowing revealed by AI camera trap monitoring

open access: yesBasic and Applied Ecology
Mowing is essential for maintaining species-rich grasslands but causes short-term mortality and habitat disruption for arthropod communities. However, mid-term recovery dynamics after mowing within the same season remain poorly understood, mainly due to ...
Robert Künast   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

User-centric Visualization of Data Provenance [PDF]

open access: yes, 2015
The need to understand and track files (and inherently, data) in cloud computing systems is in high demand. Over the past years, the use of logs and data representation using graphs have become the main method for tracking and relating information to the
Garae, Jeffery
core  

Towards Ubiquitous Brushing for Information Visualization [PDF]

open access: yes, 2006
Brushing is a collection of techniques to dynamically query and directly select elements on the visual display. Such interaction allows the user to explore the visualization, to interactively select a subset of points and see how these changes are ...
Wright, M.A.E., Roberts, J.C.
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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