Results 161 to 170 of about 8,038,699 (404)
Molecular Oncology, EarlyView.PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang +6 more
wiley +1 more source
Crystals, 2019 The crystal structure of fosfomycin tromethamine has been solved and refined using synchrotron X-ray powder diffraction data, and optimized using density functional techniques.
Zachary R. Butler +3 more
doaj +1 more source
GRAD: On Graph Database Modeling [PDF]
arXiv, 2016 Graph databases have emerged as the fundamental technology underpinning trendy application domains where traditional databases are not well-equipped to handle complex graph data. However, current graph databases support basic graph structures and integrity constraints with no standard algebra.
arxiv
Ribosomal Database Project: data and tools for high throughput rRNA analysis
Nucleic Acids Res., 2013 Ribosomal Database Project (RDP; http://rdp.cme.msu.edu/) provides the research community with aligned and annotated rRNA gene sequence data, along with tools to allow researchers to analyze their own rRNA gene sequences in the RDP framework.
J. Cole +9 more
semanticscholar +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
Freely available mean daily discharge series from Czechia: what can be inferred from them?
E3S Web of Conferences, 2017 Most hydrometeorological data from Czechia are still provided for a fee. This especially applies to time series with a finer step than monthly. The fact that the data must be paid with respect to an expert’s appraisement and that the proper licence ...
Ledvinka Ondrej
doaj +1 more source
Test Case Series 1 (Overview of Intercalibration Results: A Model Comparison) [PDF]
, 2011 Presentation Overview: Comparison of model results All comparisons (plots) are percent difference from FIAT reference ...
Thermal Performance Database Team
core +1 more source
dbSNP: the NCBI database of genetic variation
Nucleic Acids Res., 2001 In response to a need for a general catalog of genome variation to address the large-scale sampling designs required by association studies, gene mapping and evolutionary biology, the National Center for Biotechnology Information (NCBI) has established ...
S. Sherry +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
TCMSP: a database of systems pharmacology for drug discovery from herbal medicines
Journal of Cheminformatics, 2014 BackgroundModern medicine often clashes with traditional medicine such as Chinese herbal medicine because of the little understanding of the underlying mechanisms of action of the herbs. In an effort to promote integration of both sides and to accelerate
Jinlong Ru +13 more
semanticscholar +1 more source