Results 51 to 60 of about 8,999,941 (280)

RegenBase: a knowledge base of spinal cord injury biology for translational research. [PDF]

, 2016
Spinal cord injury (SCI) research is a data-rich field that aims to identify the biological mechanisms resulting in loss of function and mobility after SCI, as well as develop therapies that promote recovery after injury.
Abeyruwan, Saminda W, Al-Ali, Hassan, Bixby, John L, Callahan, Alison, Ferguson, Adam R, Lemmon, Vance P, Popovich, Phillip G, Sakurai, Kunie, Shah, Nigam H, Visser, Ubbo   +9 more
core   +2 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Firebird Database Backup by Serialized Database Table Dump [PDF]

, 2007
This paper presents a simple data dump and load utility for Firebird databases which mimics mysqldump in MySQL. This utility, fb_dump and fb_load, for dumping and loading respectively, retrieves each database table using kinterbasdb and serializes the ...
Ling, Maurice HT
core   +1 more source

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

Journal of Cheminformatics, 2014
BackgroundModern medicine often clashes with traditional medicine such as Chinese herbal medicine because of the little understanding of the underlying mechanisms of action of the herbs. In an effort to promote integration of both sides and to accelerate
Jinlong Ru, Peng Li, Jinan Wang, W. Zhou, Bohui Li, Chao Huang, Pidong Li, Zihu Guo, W. Tao, Yinfeng Yang, Xue Xu, Yan Li, Yonghua Wang, Ling Yang   +13 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

National Soils Database [PDF]

, 2007
End of project reportThe objectives of the National Soils Database project were fourfold. The first was to generate a national database of soil geochemistry to complete the work that commenced with a survey of the South East of Ireland carried out in ...
Carrigg, Cora, Carton, Owen T., Fay, Deirdre, Grennan, Eamonn J., Kramers, Gaelene, McGrath, David, O'Flaherty, Vincent, Zhang, Chaosheng   +7 more
core  

KEGG: biological systems database as a model of the real world

Nucleic Acids Research
KEGG (https://www.kegg.jp/) is a database resource for representation and analysis of biological systems. Pathway maps are the primary dataset in KEGG representing systemic functions of the cell and the organism in terms of molecular interaction and ...
M. Kanehisa, Miho Furumichi, Yoko Sato, Yuriko Matsuura, Mari Ishiguro-Watanabe   +4 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The Mental Database [PDF]

, 2005
This article uses database, evolution and physics considerations to suggest how the mind stores and processes its data. Its innovations in its approach lie in:- A) The comparison between the capabilities of the mind to those of a modern relational ...
Brown, Mr Kenneth H.
core