Results 81 to 90 of about 6,912,826 (303)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Examining HPO by organ and system to facilitate practical use by clinicians
Genomics & InformaticsThe Human Phenotype Ontology (HPO) is widely used for annotating clinical text data, and sufficient annotation is crucial for the effective utilization of clinical texts.
Eisuke Dohi +4 more
doaj +1 more source
Database independent Migration of Objects into an Object-Relational Database [PDF]
, 2002 This paper reports on the CERN-based WISDOM project which is studying the serialisation and deserialisation of data to/from an object database (objectivity) and ORACLE 9i.Comment: 26 pages, 18 figures; CMS CERN Conference Report ...
Ali, Arshad +4 more
core +1 more source
A Call to Arms: Revisiting Database Design [PDF]
, 2011 Good database design is crucial to obtain a sound, consistent database, and - in turn - good database design methodologies are the best way to achieve the right design.
Antonio Badia +8 more
core +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Crystals, 2019 Interfaces in heterostructures of crystalline materials could strongly affect the slip of dislocations. Such interfaces have become one of the most popular methods to tailor material strength and ductility.
Zhibo Zhang +5 more
doaj +1 more source
Advances in Laboratory Medicine, 2020 A lo largo de los años se han publicado numerosos artículos sobre variación biológica (VB) de diferente calidad. Los objetivos de este trabajo fueron realizar una revisión sistemática y una evaluación crítica de los estudios de VB para albúmina ...
Ricós Carmen +15 more
doaj +1 more source
, 2010 Inductive databases are usually viewed as databases that contain models, next to data, such that mining the data essentially boils down to querying them for models. This unifies data mining with database querying. In his chapter, we consider experiment databases.
Vanschoren, Joaquin, Blockeel, Hendrik
openaire +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source