Results 111 to 120 of about 219,510 (306)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Turning tools database creation

open access: yes, 2019
Volba konkrétního způsobu obrábění závisí na mnoho faktorech. Vytvoření jakékoliv součásti je tak možné mnoho způsoby. Bakalářská práce se zabývá soustružnickými nástroji a jejich databází.
Veronika Kastnerová
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Disseny d'un motor de recuperació de la informació per a ús experimental i educatiu

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2000
En aquest article es descriu el disseny i el funcionament d’un motor de recuperació d’informació basat en el model vectorial, que té la finalitat de servir de base d’experimentació en tasques d’investigació i com a recurs per a la docència.
Figuerola, Carlos G.   +2 more
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Do Small Businesses Create More Jobs? New Evidence for the United States from the National Establishment Time Series [PDF]

open access: yes
We use a new database, the National Establishment Time Series (NETS), to revisit the debate about the role of small businesses in job creation. Birch (e.g., 1987) argued that small firms are the most important source of job creation in the U.S.
Zhang, Junfu   +2 more
core  

Diseño de un motor de recuperación de la información para uso experimental y educativo

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2000
En aquest article es descriu el disseny i el funcionament d’un motor de recuperació d’informació basat en el model vectorial, que té la finalitat de servir de base d’experimentació en tasques d’investigació i com a recurs per a la docència.
Figuerola, Carlos G.   +2 more
doaj  

ESTIMATION OF THERMOPHYSICAL PROPERTIES OF VEGETABLE OILS FOR CREATION DATABASE TO ENGINEERING CALCULATIONS

open access: yesITEGAM-JETIA, 2020
Researches focusing on the development of biofuel production processes have increased significantly in recent years, mainly for environmental and economic issues.
Gisele Cristina Rabelo Silva   +1 more
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Knowledge Creation through User-Guided Data Mining: A Database Case

open access: yes, 2008
This case focuses on learning by applying the four integrating mechanisms of Nonaka\u27s knowledge creation theory: socialization, externalization, combination and internalization.
Steiger, David M.
core  

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