Results 91 to 100 of about 6,201,586 (306)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
On Instance-Completeness for Database Query Languages involving Object Creation [PDF]
, 1996 In [4, 13], Bancilhon and Paredaens introduced a notion of completeness for relational database languages on instance-level. Their criterion was subsequently called BP-completeness.
Andries, Marc +5 more
core +1 more source
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2000 Es descriuen els passos necessaris per publicar a Internet una base de dades creada amb Microsoft Access utilitzant la tecnologia ASP. Es parteix d'un exemple de base de dades creada per a controlar el procés d'adquisicions i es van resseguint, en forma ...
Rodríguez-Gairín, Josep-Manuel
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2000 Es descriuen els passos necessaris per publicar a Internet una base de dades creada amb Microsoft Access utilitzant la tecnologia ASP. Es parteix d'un exemple de base de dades creada per a controlar el procés d'adquisicions i es van resseguint, en forma ...
Rodríguez-Gairín, Josep-Manuel
doaj
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
USE OF PROSOPOGRAPHIC DATABASES IN STUDYING THE HISTORY OF EDUCATION
Вестник Кемеровского государственного университета, 2014 The paper focuses on the methods of studying and analyzing historical sources. The database “School teachers of West Siberia (1860 – 1917)” is used to exemplify the process electronic database creation: the main principles of creation are analyzed, the ...
Yu. Yu. Gizey, E. G. Isakova
doaj
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
, 2007 The Legal Threats Database is a catalog of the growing number of lawsuits, cease and desist letters, and other legal challenges faced by those engaging in online speech.
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