Results 31 to 40 of about 189,292 (258)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Development Of Scientific Content Management, Evaluation And Publication Software
MANAS: Journal of Engineering, 2018 With the development of information and communication technologies, the workflow of many processes has also changed. A scientific publication processes are also facing these changes.
A. Bolushbek, R. Ismailova
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
ENVIRONMENTAL MONITORING IN SIBERIA: APPROACHES TO CREATION OF DATABASE OF DANGEROUS WEATHER EVENTS [PDF]
Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2016 The method of subject adjustment of data of many years’ monitoring of meteorological and radiation values in urban environment was developed. Proposed method of subject adjustment of monitoring data serves to creation and updating of database of ionizing
P. M. Nagorskiy +5 more
doaj +1 more source
Creation of a children’s speech database [PDF]
The Journal of the Acoustical Society of America, 1995 Speech was recorded from a large number of children ages 5 through 18 years inclusive, at a custom installation at the St. Louis Science Center. Two separate sets of recordings were made: (1) using a high-fidelity microphone, and (2) using one of five telephone handsets.
James D. Miller +5 more
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Database “Biography” – a New Information Resource of the State Public Historical Library of Russia
Библиосфера, 2022 The article is devoted to a new information resource of the State Public Historical Library of Russia (SHPL) – the Biography database, which takes into account publications of a biographical and iconographic nature in pre-revolutionary periodicals.
K. A. Shaposhnikov
doaj +1 more source
Computer Vision and the Creation of a Database of Printers’ Ornaments
Digital Humanities Quarterly, 2021 This article describes the creation of a database of over 1 million images of eighteenth-century printers’ ornaments (or fleurons) using computer vision, and how the database was refined using machine learning. The successes and limitations of the method used are discussed, and the purpose of the database for research in the humanities is outlined. The
Hazel Wilkinson +2 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source