Results 81 to 90 of about 4,269,596 (312)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Full-text database “Outstanding soil scientists of Russia”: creation, purpose and use

Бюллетень Почвенного института им. В.В. Докучаева
The full-text problem-oriented database “Outstanding Soil Scientists of Russia” (DB), created by the Federal State Budgetary Scientific Institution “Central Scientific Agricultural Library” (CSAL), for the purpose of providing information for scientific ...
M. S. Bunin, I. A. Kolenchenko, L. N. Pirumova, A. Yu. Nepochatykh, E. P. Kadilina   +4 more
doaj   +1 more source

Job Creation and Destruction in Northern Ireland - 1973-1993 [PDF]

Job creation and destruction estimates are made for Northern Ireland manufacturing using the ARD database. International comparisons suggest job creation and destruction rates in Northern Ireland were below those elsewhere. Job turnover rates exhibit the
Stephen Roper
core  

Creation of the web-based database of maser sources [PDF]

, 2018
Для решения проблемы поиска и систематизации данных по астрономическим мазерным источникам был создан программный код, работающий в режиме онлайн, предназначенный для хранения, анализа и визуализации данных о мазерных источниках.
Ladeyschikov, D. A., Nakashima, J., Nogin, S. A., Sobolev, A. M., Ладейщиков, Д. А., Накасима, Д., Ногин, С. А., Соболев, А. М.   +7 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Optical measurements of paintings and the creation of an artwork database for authenticity.

PLoS ONE, 2017
Paintings have high cultural and commercial value, so that needs to be preserved. Many techniques have been attempted to analyze properties of paintings, including X-ray analysis and optical coherence tomography (OCT) methods, and enable conservation of ...
Seonhee Hwang, Hyerin Song, Soon-Woo Cho, Chang Eun Kim, Chang-Seok Kim, Kyujung Kim   +5 more
doaj   +1 more source

Creation of Database of Cutting Tools [PDF]

, 2016
Import 02/11/2016Náplní bakalářské práce je tvorba databáze řezných nástrojů. Teoretická část se zabývá problematikou správy řezných nástrojů a využití softwarové podpory pro jejich správu.
Blanarovič, Ladislav
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

APPLICATION OF BIM IN THE CREATION OF PREFABRICATED STRUCTURES LOCAL PARAMETERIZED COMPONENT DATABASE

Architecture and Engineering, 2019
Introduction: As a research focus in the construction industry in recent years, prefabricated structures have advantages such as environmentally friendly and economical and so on, but it also increases the complexity of design and construction and the ...
Qinghan Bai, Sihua Deng, Chenguang Li, Ze Qie   +3 more
doaj   +1 more source