Results 101 to 110 of about 3,236,092 (351)
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Contributions to Logical Database Design [PDF]
Informatică economică, 2012 This paper treats the problems arising at the stage of logical database design. It comprises a synthesis of the most common inference models of functional dependencies, deals with the problems of building covers for sets of functional dependencies, makes
Vitalie COTELEA
doaj
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Using Fuzzy Logic to Evaluate Normalization Completeness for An Improved Database Design
, 2012 A new approach, to measure normalization completeness for conceptual model, is introduced using quantitative fuzzy functionality in this paper. We measure the normalization completeness of the conceptual model in two steps.
Iqbal, Nayyar +2 more
core +1 more source
Dynamic Database Design of Sports Quality Based on Genetic Data Algorithm and Artificial Intelligence. [PDF]
Comput Intell Neurosci, 2022 Yue Q.
europepmc +1 more source
The Relational Database Aspects of Argonne's ATLAS Control System [PDF]
eConf C011127 (2001) WEAP066, 2001 The Relational Database Aspects of Argonnes ATLAS Control System Argonnes ATLAS (Argonne Tandem Linac Accelerator System) control system comprises two separate database concepts. The first is the distributed real-time database structure provided by the commercial product Vsystem [1].
arxiv
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Investigation of IGES for CAD/CAE data transfer [PDF]
In a CAD/CAE facility there is always the possibility that one may want to transfer the design graphics database from the native system to a non-native system. This may occur because of dissimilar systems within an organization or a new CAD/CAE system is
Zobrist, George W.
core +1 more source
Facilitating evolution in relational database design : a procedure to evaluate and refine novice database designers' schemata : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Information Systems at Massey University [PDF]
, 1996 Relational database management systems (RDBMS) have become widely used by many industries in recent years. Latterly these systems have begun to expand their market by becoming readily available at minimal cost to most users of modern computing technology.
Ryder, Michael Robert
core