Results 81 to 90 of about 14,745,777 (301)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Journal of Innovation Information Technology and ApplicationThe amount of data stored in magnetic disks (e.g., floppy disks) increases by 100% each year for each department in a company, necessitating efforts to maintain an optimal database system.
Juanda Hakim Lubis +3 more
doaj +1 more source
Perspectives on the Role of Business Rules in Database Design [PDF]
Database Systems Journal, 2012 Business rules are at the foundation of every information system as they drive and offer guidelines for managing and conducting all activities within an organizations.
Anca Ioana ANDREESCU, Marinela MIRCEA
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Dynamic Database Design of Sports Quality Based on Genetic Data Algorithm and Artificial Intelligence. [PDF]
Comput Intell Neurosci, 2022 Yue Q.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The architecture of an autonomic, resource-aware, workstation-based distributed database system [PDF]
, 2012 Distributed software systems that are designed to run over workstation machines within organisations are termed workstation-based. Workstation-based systems are characterised by dynamically changing sets of machines that are used primarily for other ...
Macdonald, Angus
core +2 more sources
Regression-Based Performance Prediction in Asphalt Mixture Design and Input Analysis with SHAP
Applied SciencesThe primary aim of this study is to predict the Marshall stability and flow values of hot-mix asphalt samples prepared according to the Marshall design method using regression-based machine learning algorithms.
Kemal Muhammet Erten, Remzi Gürfidan
doaj +1 more source
NORMALIZATION IN DATABASE DESIGN
Jurnal CoreIT: Jurnal Hasil Penelitian Ilmu Komputer dan Teknologi Informasi, 2018 This research is done to find a simple solution how to find a normalization techniques are appropriate in database design, normalization techniques has several steps of which are forms of abnormal, normalization first, normalization 2st and normalization
Zainul Efendy
doaj +1 more source