Results 171 to 180 of about 15,215,863 (336)

Applications of fuzzy languages and pictorial databases to decision support systems design [PDF]

, 1983
Edward T. Lee
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Subquery allocations in distributed databases using genetic algorithms

Journal of Computer Science and Technology, 2010
Minimization of query execution time is an important performance objective in distributed databases design. While total time is to be minimized for On Line Transaction Processing (OLTP) type queries, response time has to be minimized in Decision Support ...
Narasimhaiah Gorla, Suk-Kyu Song
doaj  

Case study: the analysis, design & implementation of a database conversion [PDF]

, 1988
Vivie G. Babb
openalex   +1 more source

Design and implementation of national security vulnerability database

Tongxin xuebao, 2011
Base on both domestic and overseas research on vulnerability database,considering our national conditions and the security requirements,a security vulnerability database model was proposed.It’s compatible with multiple stan-dards,and could be used to ...
ZHANG Yu-qing1, WU Shu-ping1, LIU Qi-xu1, LIANG Fang-fang1   +3 more
doaj   +2 more sources

GEOGRAPHICAL INFORMATION SYSTEMS AND THE DURABLE CONSTRUCTION OF URBAN AND RURAL ENVIRONMENTS [PDF]

The idea of basis is the present condition and developing trend of cadastral management Valcea. The paper expatiates on the construction status of the Cadastral Management Information System on Integration of Urban and Rural area of Valcea.
Carmen RADUT
core  

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

FEBS Open Bio, EarlyView.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques, Edit Ábrahám, Hiromi Muramatsu, Daniel Youssef Bargieri, Norbert Pardi, Zoltán Lipinszki   +5 more
wiley   +1 more source

Physical design equivalencies in database conversion [PDF]

, 1990
Mark L. Gillenson
openalex   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

NeurDB: On the Design and Implementation of an AI-powered Autonomous Database [PDF]

CIDR 2025
Databases are increasingly embracing AI to provide autonomous system optimization and intelligent in-database analytics, aiming to relieve end-user burdens across various industry sectors. Nonetheless, most existing approaches fail to account for the dynamic nature of databases, which renders them ineffective for real-world applications characterized ...
arxiv