Results 171 to 180 of about 16,804,247 (357)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Design and implementation of national security vulnerability database

Tongxin xuebao, 2011
Base on both domestic and overseas research on vulnerability database,considering our national conditions and the security requirements,a security vulnerability database model was proposed.It’s compatible with multiple stan-dards,and could be used to ...
ZHANG Yu-qing1, WU Shu-ping1, LIU Qi-xu1, LIANG Fang-fang1   +3 more
doaj  

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Applying Vertical Fragmentation Techniques in Logical Design of Multidimensional Databases [PDF]

, 2000
Matteo Golfarelli, Dario Maio, Stefano Rizzi   +2 more
openalex   +1 more source

A new generation of the United States National Land Cover Database: Requirements, research priorities, design, and implementation strategies

Isprs Journal of Photogrammetry and Remote Sensing, 2018
Limin Yang, Suming Jin, P. Danielson, C. Homer, L. Gass, S. Bender, Adam Case, Catherine Costello, J. Dewitz, J. Fry, Michelle Funk, B. Granneman, G. Liknes, M. Rigge, G. Xian   +14 more
semanticscholar   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Applications of fuzzy languages and pictorial databases to decision support systems design

, 1983
Edward T. Lee
openalex   +1 more source

Multiparadigm design of a simple relational database [PDF]

, 2000
Charles D. Knutson, Timothy A. Budd, Hugh Vidos   +2 more
openalex   +1 more source