Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
<i>OncoSolidDB</i>: An Oncology-Focused Curated Database of Ligand-Target Interactions for Precision Medicine Across Major Solid Cancers. [PDF]
Khamessi O +3 more
europepmc +1 more source
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source
Technology-enabled sexual health promotion for individuals with intellectual and developmental disabilities: protocol for a scoping review. [PDF]
P James C +4 more
europepmc +1 more source
High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello +5 more
wiley +1 more source
Achieving Achromatic and Misalignment-Tolerant Fiber Coupling via Meta-Lens with Structural Interleaving. [PDF]
Yuan X +7 more
europepmc +1 more source
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch +6 more
wiley +1 more source
Resources and applications of public biomedical data. [PDF]
Liu M +9 more
europepmc +1 more source
ONYX: an alignment-free biological sex inference from high-throughput sequencing data. [PDF]
Ishiya K.
europepmc +1 more source
Manufacturer and User Facility Device Experience (MAUDE)-Dash: An open-source, interactive dashboard for real-time post-market surveillance of medical devices. [PDF]
Porwal MH.
europepmc +1 more source

