Results 71 to 80 of about 15,215,863 (336)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Enabling On-Demand Database Computing with MIT SuperCloud Database Management System [PDF]
, 2015 The MIT SuperCloud database management system allows for rapid creation and flexible execution of a variety of the latest scientific databases, including Apache Accumulo and SciDB. It is designed to permit these databases to run on a High Performance Computing Cluster (HPCC) platform as seamlessly as any other HPCC job.
arxiv +1 more source
Physical design of temporal databases [PDF]
, 1988 The primary focus of research into temporal databases has been on logical data modeling. Yet, the feasibility of implementing such databases depends as much on the development of retrieval and storage structures that are suited to the unique nature of temporal data.
Gunadhi, H, Segev, A
openaire +4 more sources
A database to enable discovery and design of piezoelectric materials
Scientific Data, 2015 Piezoelectric materials are used in numerous applications requiring a coupling between electrical fields and mechanical strain. Despite the technological importance of this class of materials, for only a small fraction of all inorganic compounds which ...
Maarten de Jong +4 more
semanticscholar +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Analisis dan Perancangan Basis Data dan Aplikasi Pegadaian pada PT Langitan Segi Putera
ComTech, 2012 This article contains analysis and design of pawnshop database systems and its application design that can be used by PT Langitan Segi Putera for acquiring information about pawn goods, decision making in pawnshop system, how to increase the ...
Diana Diana
doaj +1 more source
Managing Variability in Relational Databases by VDBMS [PDF]
arXiv, 2019 Variability inherently exists in databases in various contexts which creates database variants. For example, variants of a database could have different schemas/content (database evolution problem), variants of a database could root from different sources (data integration problem), variants of a database could be deployed differently for specific ...
arxiv
An Empirical Study on the Design and Evolution of NoSQL Database Schemas [PDF]
arXiv, 2020 We study how software engineers design and evolve their domain model when building applications against NoSQL data stores. Specifically, we target Java projects that use object-NoSQL mappers to interface with schema-free NoSQL data stores. Given the source code of ten real-world database applications, we extract the implicit NoSQL database schema.
arxiv
Benchmarking Specialized Databases for High-frequency Data [PDF]
arXiv, 2023 This paper presents a benchmarking suite designed for the evaluation and comparison of time series databases for high-frequency data, with a focus on financial applications. The proposed suite comprises of four specialized databases: ClickHouse, InfluxDB, kdb+ and TimescaleDB. The results from the suite demonstrate that kdb+ has the highest performance
arxiv
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source