Results 81 to 90 of about 3,287,729 (314)

An integrated database with system optimization and design features [PDF]

open access: yes
A customized, mission-specific relational database package was developed to allow researchers working on the Mars oxygen manufacturing plant to enter physical description, engineering, and connectivity data through a uniform, graphical interface and to ...
Arabyan, A.   +2 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

دراسة في استخدام اسلوب قاعدة المعلومات في تصميم نظام اجازات المركبات

open access: yesIraqi Journal for Computers and Informatics, 1980
الغرض تطوير العمل في مديرية المرور العامة / مكتب التسجيل ، قام المركز القومي للاستشارات والتطوير الاداري بأجراء دراسة النظامي اجازات السوق والمركبات وقدم تقريرا بذلك في مارس 1976 تضمن عدد من البدائل والتوصيات لتطوير العمل اليدوي لكلا النظامين إلا أن هذه ...
هند فتح الله قندلا
doaj   +1 more source

Examples of finite element mesh generation using SDRC IDEAS [PDF]

open access: yes, 1990
IDEAS (Integrated Design Engineering Analysis Software) offers a comprehensive package for mechanical design engineers. Due to its multifaceted capabilities, however, it can be manipulated to serve the needs of electrical engineers, also.
Volakis, John L., Zapp, John
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

The ISSPP PIPAC database: design, process, access, and first interim analysis. [PDF]

open access: yesPleura Peritoneum, 2021
Mortensen MB   +9 more
europepmc   +1 more source

A rudimentary database for three-dimensional objects using structural representation [PDF]

open access: yes
A database which enables users to store and share the description of three-dimensional objects in a research environment is presented. The main objective of the design is to make it a compact structure that holds sufficient information to reconstruct the
Sowers, James P.
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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