Results 101 to 110 of about 3,107,135 (285)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
A Stock Market Prediction Method Based on Support Vector Machines (SVM) and Independent Component Analysis (ICA) [PDF]
Database Systems Journal, 2016 The research presented in this work focuses on financial time series prediction problem. The integrated prediction model based on support vector machines (SVM) with independent component analysis (ICA) (called SVM-ICA) is proposed for stock market ...
Hakob GRIGORYAN
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Optimized Data Indexing Algorithms for OLAP Systems [PDF]
Database Systems Journal, 2010 The need to process and analyze large data volumes, as well as to convey the information contained therein to decision makers naturally led to the development of OLAP systems.
Lucian BORNAZ
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Big Data and Specific Analysis Methods for Insurance Fraud Detection [PDF]
Database Systems Journal, 2014 Analytics is the future of big data because only transforming data into information gives them value and can turn data in business in competitive advantage.
Ramona BOLOGA +2 more
doaj
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Big Data, indispensable today [PDF]
Database Systems Journal, 2015 Big data is and will be used more in the future as a tool for everything that happens both online and offline. Of course , online is a real hobbit, Big Data is found in this medium , offering many advantages , being a real help for all consumers. In this
Radu-Ioan ENACHE, Marian Adrian ENE
doaj
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Customizing GPT for natural language dialogue interface in database access
Genomics & InformaticsThe paper presents Anatomy3DExplorer, a customized ChatGPT designed as a natural language dialogue interface for exploring 3D models of anatomical structures.
Jin-Dong Kim, Kousaku Okubo
doaj +1 more source