In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Learning From User-Specified Optimizer Hints in Database Systems
Recently, numerous machine learning (ML) techniques have been applied to address database performance management problems, including cardinality estimation, cost modeling, optimal join order prediction, hint generation, etc.
Zakrzewicz Maciej
doaj +1 more source
Factors Affecting the Adoption of Online Database Systems for Learning among Students at Economics Universities in Vietnam. [PDF]
Nguyen TMP.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Most modern-day organizations have a need to record data relevant to their everyday activities and many choose to organise and store some of this information in an electronic database.
Beynon-Davies, Paul
core
Advances in database systems education: Methods, tools, curricula, and way forward. [PDF]
Ishaq M +6 more
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Electronic Phenotype for Advanced Chronic Kidney Disease in a Veteran Health Care System Clinical Database: Systems-Based Strategy for Model Development and Evaluation. [PDF]
Chamarthi G +6 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Forensic data management and database systems in forensic investigations for cases of missing and unidentified persons in Brazil. [PDF]
Calmon M.
europepmc +1 more source

