Results 141 to 150 of about 9,715,830 (339)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Embedding Relational Databases in Object Ontologies: Implementation Issues

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2014
In this paper the problem of database embedding in logical knowledge management environment is considered. The approaches to the implementation of database embedding in ontologies are established through their modeling based on object theories.
I.A. Kazakov   +2 more
doaj  

Machine learning study of universal electronic stopping cross-sections of ions in matter

open access: yesNuclear Engineering and Technology
Accurate electronic stopping cross-section (ESCS) database of ions in matter is crucial for precise simulation of radiation damage. Based on the experimental-cleaned database of SRIM, binary theory and unitary convolution approximation as well as the ...
Fan Cheng   +5 more
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

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