Results 121 to 130 of about 287,498 (311)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Transition Probabilities, Oscillator and Line Strengths in Sc XIX

open access: yesEast European Journal of Physics
Scandium XIX ion is a member of the isoelectronic sequence of Li-like ions. Numerical coulomb approximation and quantum defect theory have been used to calculate energies, quantum defects & transition probabilities, oscillator, and line strengths of Sc ...
Zaheer Uddin   +3 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Representing fuzzy decision tables in a fuzzy relational database environment. [PDF]

open access: yes
In this paper the representation of decision tables in a relational database environment is discussed. First, crisp decision tables are defined. Afterwards a technique to represent decision tables in a relational system is presented.
Vanthienen, Jan, Wets, G, Chen, G
core  

TO PROBLEM CONCERNING FORMATION OF DATABASE ON TPS PRIMARY EQUIPMENT RELIABILITY

open access: yesНаука и техника, 2012
The paper shows main approaches accepted for formation of database on reliability of heat-power equipment applied at thermal power stations. The used methods of probability theory and up-to-date computer technologies have made it possible to develop ...
A. L. Burov   +2 more
doaj  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Database Theory in Action: Search-Based Program Optimization [PDF]

open access: yes
Recent work in programming languages developed an approach to term rewritings based on equality saturation (EqSat), which, instead of applying destructively the rewrite rules, maintains all equivalent expressions in a structure called an E-graph.
Willsey, Max   +3 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Database Theory in Action: Cypher, GQL, and Regular Path Queries [PDF]

open access: yes
Cypher has so far been the most commonly used query language for property graphs, and served as the foundation of the recently standardized graph query language GQL.
Libkin, Leonid   +3 more
core   +1 more source

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