Results 1 to 10 of about 2,679,408 (299)
A Novel Automatic Relational Database Normalization Method
Acta Informatica Pragensia, 2022 The increase in data diversity and the fact that database design is a difficult process make it practically impossible to design a unique database schema for all datasets encountered.
Emre Akadal, Mehmet Hakan Satman
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BMC Genomics, 2023 Background Chinese indigenous pigs in Yunnan exhibit considerable phenotypic diversity, but their population structure and the biological interpretation of signatures of artificial selection require further investigation.
Xueyan Feng +9 more
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The art of curation at a biological database: Principles and application
Current Plant Biology, 2017 The variety and quantity of data being produced by biological research has grown dramatically in recent years, resulting in an expansion of our understanding of biological systems. However, this abundance of data has brought new challenges, especially in
Sarah G. Odell +4 more
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npj Genomic Medicine, 2023 Von Willebrand disease (VWD) is a common bleeding disorder caused by mutations in the von Willebrand factor gene (VWF). The true global prevalence of VWD has not been accurately established.
Omid Seidizadeh +4 more
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GSD: a genetic screen database
Mechanisms of Development, 2004 The systematic assignment of gene function to a sequenced genome is one of the outstanding challenges in the post-genomic era. Large-scale systematic mutagenesis screens are important tools for reaching this goal. Here we describe GSD, a software package that allows storage and integration of data from genetic screens. GSD was initially developed for a
Henrich, Thorsten +6 more
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Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: Despite advances in precision medicine and understanding of the molecular pathways, melanoma remains the deadliest skin cancer, warranting identification of novel biomarkers.
Reid McCallister +3 more
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Orphanet Journal of Rare Diseases, 2022 Background ENPP1 Deficiency—caused by biallelic variants in ENPP1—leads to widespread arterial calcification in early life (Generalized Arterial Calcification of Infancy, GACI) or hypophosphatemic rickets in later life (Autosomal Recessive ...
Lauren M. Chunn +6 more
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A taxonomic schema of potential pitfalls in clinical variant analysis based on real-world evidence.
PLoS ONE, 2023 The classification and interpretation of genetic variants associated with genetic diseases have been shown to vary between clinical genetic laboratories. This can lead to errors introduced in the interpretation and public presentation of genetic findings
Adam Coovadia +3 more
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A genetic algorithm for database query optimization [PDF]
Proceedings of the First IEEE Conference on Evolutionary Computation. IEEE World Congress on Computational Intelligence, 2002 Numerous decision support applications have been modeled as set covering and partitioning problems. We propose an extension to the database query language SQL to enable applications of these problems to be stated and solved directly by the database system.
Horng, Jorng-Tzong +2 more
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Prototyping a genetics deductive database.
Proceedings. International Conference on Intelligent Systems for Molecular Biology, 1994 We are developing a laboratory notebook system known as the Genetics Deductive Database. Currently our prototype provides storage for biological facts and rules with flexible access via an interactive graphical display. We have introduced a formal basis for the representation and reasoning necessary to order genome map data and handle the uncertainty ...
C. Hearne +3 more
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