On the automated extraction of regression knowledge from databases [PDF]
, 1993 The advent of inexpensive, powerful computing systems, together with the increasing amount of available data, conforms one of the greatest challenges for next-century information science.
Muruzábal, Jorge
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Evolving Takagi-Sugeno-Kang fuzzy systems using multi-population grammar guided genetic programming [PDF]
This work proposes a novel approach for the automatic generation and tuning of complete Takagi-Sugeno-Kang fuzzy rule based systems. The examined system aims to explore the effects of a reduced search space for a genetic programming framework by means of
Tsakonas, Athanasios, Gabrys, Bogdan
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Implementation Of Mediator-Based Integration System For A Transparent Access To Multiple Biological Databases. [PDF]
, 2007 Existing biological databases seem to function independently from each other. Different organizations and research group, build customised databases with different formats for collecting biological data through their ...
Anwar, Muhammad Fairuz, Husain, Wahidah
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Biomedical ethics and genetic epidemiology [PDF]
, 2004 Biomedical ethics developed in the late twentieth century as a challenge to the self- regulatory ethic that previously governed medical practice. Yet in recent years bioethics has come under scrutiny from the social sciences, which claim that the field ...
Whong-Barr, Michael
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Nutrigenomics, individualism and public health. [PDF]
, 2004 Issues arising in connection with genes and nutrition policy include both nutrigenomics and nutrigenetics. Nutrigenomics considers the relationship between specifc nutrients or diet and gene expression and, it is envisaged, will facilitate prevention of ...
Chadwick, Ruth
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A Genetic Programming Framework for Two Data Mining Tasks: Classification and Generalized Rule Induction [PDF]
, 1997 This paper proposes a genetic programming (GP) framework for two major data mining tasks, namely classification and generalized rule induction. The framework emphasizes the integration between a GP algorithm and relational database systems. In particular,
Alex A. Freitas, Freitas, Alex A.
core
A survey of genetic improvement search spaces [PDF]
, 2019 Genetic Improvement (GI) uses automated search to improve existing software. Most GI work has focused on empirical studies that successfully apply GI to improve software's running time, fix bugs, add new features, etc. There has been little research into
Alexander, B +17 more
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