Results 91 to 100 of about 5,928,974 (349)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Graphical interface to the genetic network database GeNet. [PDF]
Bioinformatics, 1998 Abstract SUMMARY: We designed a Java applet which enables the visualization of genetic networks and can be used as a Web publishing tool by molecular biologists studying the mechanisms of gene interactions. AVAILABILITY: http://www.
V N, Serov, A V, Spirov, M G, Samsonova
openaire +2 more sources
Nucleic Acids Res., 2018 Successful development of biological databases requires accommodation of the burgeoning amounts of data from high-throughput genomics pipelines. As the volume of curated data in Animal QTLdb (https://www.animalgenome.org/QTLdb) increases exponentially ...
Zhi-Liang Hu, Carissa A. Park, J. Reecy
semanticscholar +1 more source
IndiGenomes: a comprehensive resource of genetic variants from over 1000 Indian genomes
Nucleic Acids Research, 2020 With the advent of next-generation sequencing, large-scale initiatives for mining whole genomes and exomes have been employed to better understand global or population-level genetic architecture.
Abhinav R Jain +50 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Genetic Programming for Multibiometrics
, 2012 Biometric systems suffer from some drawbacks: a biometric system can provide in general good performances except with some individuals as its performance depends highly on the quality of the capture. One solution to solve some of these problems is to use
Giot, Romain, Rosenberger, Christophe
core +3 more sources
Nucleic Acids Res., 2016 The MalaCards human disease database (http://www.malacards.org/) is an integrated compendium of annotated diseases mined from 68 data sources. MalaCards has a web card for each of ∼20 000 disease entries, in six global categories.
N. Rappaport +9 more
semanticscholar +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Conservation of genetic resources in the Cucurbitaceae family in Bulgaria
Растениевъдни науки, 2013 A rich collection of 2014 local and introduced accessions from Cucurbitaceae family is supported at the Institute of Plant Genetic Resources in Sadovo. Local forms are collected from different regions in North and South Bulgaria.
Stefan Neykov +3 more
doaj
DNA databanks and consent: A suggested policy option involving an authorization model
BMC Medical Ethics, 2003 Background Genetic databases are becoming increasingly common as a means of determining the relationship between lifestyle, environmental exposures and genetic diseases.
Daar Abdallah +2 more
doaj +1 more source