Results 101 to 110 of about 5,928,974 (349)
GMEnzy: A Genetically Modified Enzybiotic Database
PLoS ONE, 2014 GMEs are genetically modified enzybiotics created through molecular engineering approaches to deal with the increasing problem of antibiotic resistance prevalence. We present a fully manually curated database, GMEnzy, which focuses on GMEs and their design strategies, production and purification methods, and biological activity data.
Hongyu Wu +4 more
openaire +4 more sources
Human Mutation, 2012 The inherited cerebellar ataxias are a diverse group of clinically and genetically heterogeneous neurodegenerative disorders. Inheritance patterns of these disorders can be complex with autosomal dominant, autosomal recessive, X‐linked, and mitochondrial
J. Hersheson, A. Haworth, H. Houlden
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Clinical MedicineIntroduction: Cisplatin is a widely used chemotherapeutic agent for treating various malignancies. However, its clinical utility is often restricted by toxicities, such as nephrotoxicity, neurotoxicity and ototoxicity.1 Identifying genetic factors ...
Suvam Banerjee
doaj +1 more source
An investigation of genetic algorithm-based feature selection techniques applied to keystroke dynamics biometrics [PDF]
, 2019 Due to the continuous use of social networks, users can be vulnerable to online situations such as paedophilia treats. One of the ways to do the investigation of an alleged pedophile is to verify the legitimacy of the genre that it claims. One possible
Da Costa Abreu, Marjory +3 more
core
ToxGen: An improved reference database for the identification of type B-trichothecene genotypes in Fusarium [PDF]
, 2017 Type B trichothecenes, which pose a serious hazard to consumer health, occur worldwide in grains. These mycotoxins are produced mainly by three different trichothecene genotypes/chemotypes: 3ADON (3-acetyldeoxynivalenol), 15ADON (15-acetyldeoxynivalenol)
Abarenkov, Kessy +10 more
core +5 more sources
Research applications of primary biodiversity databases in the digital age
bioRxiv, 2019 We are in the midst of unprecedented change—climate shifts and sustained, widespread habitat degradation have led to dramatic declines in biodiversity rivaling historical extinction events.
J. Ball-Damerow +8 more
semanticscholar +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A core genetic module : the Mixed Feedback Loop
, 2005 The so-called Mixed Feedback Loop (MFL) is a small two-gene network where protein A regulates the transcription of protein B and the two proteins form a heterodimer.
B. Alberts +9 more
core +1 more source
QueryOR: a comprehensive web platform for genetic variant analysis and prioritization [PDF]
, 2017 Background: Whole genome and exome sequencing are contributing to the extraordinary progress in the study of human genetic variants. In this fast developing field, appropriate and easily accessible tools are required to facilitate data analysis. Results:
ANGLANI, FRANCA +14 more
core +3 more sources