Results 171 to 180 of about 5,302,158 (304)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Ethical, Social and Policy Aspects of Forensic Genetics: A Systematic Review

open access: yes, 2014
The EUROFORGEN Network of Excellence has brought together some of the leading individuals and groups in European forensic genetic research in order to extend existing collaborations as well as improve knowledge of innovations in this field of research ...
EUROFORGEN-NoE   +2 more
core  

Identifying missing people in the National Database of Genetic Profiles for Application in Judicial Investigation —CODIS—: Two case reports

open access: yesCase Reports, 2015
Armed conflict in Colombia has played an important role in the missing people phenomenon, in which the Government has the duty to identify, recover and investigate the crime in the process of the victims’ reparation.
Ruth Marlén Figueroa Franco   +1 more
doaj  

A sugarcane genetic database

open access: yes, 2001
A database is being built to rationalise storage and to improve accessibility to breeding and genetic data on sugarcane germplasm. It aims to gather pedigree information, agronomic information and also information on sugarcane genetic maps (AFLP genetic maps, QTL information, AFLP reference patterns, and microsatellite characteristics).
Raboin, Louis-Marie, D'Hont, Angélique
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Privacy, confidentiality and genetic databases, a modified rights approach

open access: yes, 2001
grantor: University of TorontoThe Human Genome Project has the potential to bring about enormous benefits to medicine. Large scale databases of genetic information and material serve an important function in advancing the knowledge brought ...
McIlroy, Elaine Christina
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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