Results 171 to 180 of about 5,302,158 (304)
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Ethical, Social and Policy Aspects of Forensic Genetics: A Systematic Review
The EUROFORGEN Network of Excellence has brought together some of the leading individuals and groups in European forensic genetic research in order to extend existing collaborations as well as improve knowledge of innovations in this field of research ...
EUROFORGEN-NoE +2 more
core
Armed conflict in Colombia has played an important role in the missing people phenomenon, in which the Government has the duty to identify, recover and investigate the crime in the process of the victims’ reparation.
Ruth Marlén Figueroa Franco +1 more
doaj
A database is being built to rationalise storage and to improve accessibility to breeding and genetic data on sugarcane germplasm. It aims to gather pedigree information, agronomic information and also information on sugarcane genetic maps (AFLP genetic maps, QTL information, AFLP reference patterns, and microsatellite characteristics).
Raboin, Louis-Marie, D'Hont, Angélique
openaire +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Privacy, confidentiality and genetic databases, a modified rights approach
grantor: University of TorontoThe Human Genome Project has the potential to bring about enormous benefits to medicine. Large scale databases of genetic information and material serve an important function in advancing the knowledge brought ...
McIlroy, Elaine Christina
core +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source

