New therapeutic targets and mechanisms of papillary thyroid carcinoma identified by multi-omics analysis. [PDF]
Xu J, Gao C.
europepmc +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
Bioinformatics Approach to Identifying Molecular Targets of Isoliquiritigenin Affecting Chronic Obstructive Pulmonary Disease: A Machine Learning Pharmacology Study. [PDF]
Huang S, Zhang L, Liu X.
europepmc +1 more source
Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani+2 more
wiley +1 more source
Response to letter to editor "On 'Bioinformatics in Russia: history and present-day landscape' by M.A. Nawaz, I.E. Pamirsky, and K.S. Golokhvast" by Mikhail Gelfand. [PDF]
Nawaz MA, Pamirsky IE, Golokhvast KS.
europepmc +1 more source
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
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Metaproteomics in the One Health framework for unraveling microbial effectors in microbiomes. [PDF]
Heyer R+20 more
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Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan+4 more
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In-silico discovery of type-2 diabetes-causing host key genes that are associated with the complexity of monkeypox and repurposing common drugs. [PDF]
Ajadee A+5 more
europepmc +1 more source
Multi‐Scaled Cellulosic Nanonetworks from Tunicates
Microbial and plant nanonetworks of cellulose have enabled a wide range of high‐performance yet sustainable materials. Herein, a third class of cellulosic nanonetworks is showcased by exploiting the only animal tissue‐producing cellulose nanofibers, i.e., ascidians. An ultrastructure including spherical cells and a microvasculature with diameters of 50–
Mano Govindharaj+10 more
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