Results 51 to 60 of about 1,123,563 (249)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Scalable Semi-Supervised Graph Learning Techniques for Anti Money Laundering
IEEE AccessMoney laundering is the process by which criminals move large sums of illicit money to hidden locations and integrate them as legal funds through existing financial services.
Md. Rezaul Karim +4 more
doaj +1 more source
Sensors, 2020 Process model comprehension is essential in order to understand the five Ws (i.e., who, what, where, when, and why) pertaining to the processes of organizations. However, research in this context showed that a proper comprehension of process models often
Michael Winter +3 more
doaj +1 more source
Predicting the presence of tinnitus using ecological momentary assessments
Scientific Reports, 2023 Mobile applications have gained popularity in healthcare in recent years. These applications are an increasingly important pillar of public health care, as they open up new possibilities for data collection and can lead to new insights into various ...
Marius Breitmayer +8 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Energy and AIGiven the inherent fluctuation of photovoltaic (PV) generation, accurately forecasting solar power output and grid feed-in is crucial for optimizing grid operations.
Pascal Riedel +4 more
doaj +1 more source
Bioinformation, 2011 Glaucoma, a complex heterogenous disease, is the leading cause for optic nerve-related blindness worldwide. Primary open angle glaucoma (POAG) is the most common subset and by the year 2020 it is estimated that approximately 60 million people will be affected. MYOC, OPTN, CYP1B1 and WDR36 are the important candidate genes.
Rangachari, K +6 more
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Nature Cell Biology, 2006 Although the flood of cell biological knowledge rises relentlessly, many databases face an uncertain future. Unless funding for essential bioinformatic resources is set in stone, the next storm may wash away the foundation of future cell biology research.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source