Results 61 to 70 of about 1,729,857 (317)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Thermodynamic Database Database
Calphad, 2018 Abstract This paper describes an effort to organize the condensed phases thermodynamic data freely available in electronic form within the scientific literature through the design of a special-purpose search engine indexing data electronically available in the “thermodynamic database” (TDB) format.
Axel van de Walle +2 more
openaire +1 more source
Durative Events in Active Databases [PDF]
, 2004 Active databases are DBMS which are able to detect certain events in the environment and trigger actions in consequence. Event detection has been subject of much research, and a number of different event specification languages is extant.
Augusto, Juan Carlos +3 more
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Revisiting the formal foundation of Probabilistic Databases [PDF]
, 2015 One of the core problems in soft computing is dealing with uncertainty in data. In this paper, we revisit the formal foundation of a class of probabilistic databases with the purpose to (1) obtain data model independence, (2) separate metadata on ...
van Keulen, Maurice; id_orcid +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Index Selection in Relational Databases [PDF]
, 1993 Intending to develop a tool which aims to support the physical design of relational databases can not be done without considering the problem of index selection.
Blanken, Henk +5 more
core +1 more source
Methods of working with pharmacovigilance signals
Качественная клиническая практика, 2018 This article is about the efficiency of web based systems for pharmacovigilance (PV) processes management in connection with pharmacovigilance signals based on case study of the implementation of Flex Databases PV system.
O. A. Loginovskaya +7 more
doaj
Scalable Semi-Supervised Graph Learning Techniques for Anti Money Laundering
IEEE AccessMoney laundering is the process by which criminals move large sums of illicit money to hidden locations and integrate them as legal funds through existing financial services.
Md. Rezaul Karim +4 more
doaj +1 more source