Results 101 to 110 of about 1,096,754 (353)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A Page of the Poetic Dialogue Between S.A. Yesenin and N.A. Klyuev: About the Dating of the Poem “Beloved Land! My Heart Dreams of...” [PDF]

open access: yesЛитературный факт
The article consistently examines the stages of the creative history of S.A. Yesenin’s poem “Beloved Land! My Heart Dreams of...”. For the first time, we reproduce a facsimile of the autograph of the first version of the work (from the album of the ...
Svetlana A. Seregina, Sergey I. Subbotin
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Religiosity and Relationship Quality of Dating Relationships: Examining Relationship Religiosity as a Mediator

open access: yesReligions, 2017
Individual and romantic partner religiosity are positively associated with marital quality. However, many studies focus on married couples, rather than examining dating relationships, and rely on single-item measures of religiosity. More importantly, few
Michael Langlais, Siera Schwanz
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Il «Roi de Sicile» di Adam de la Halle: una nuova proposta di datazione e localizzazione

open access: yesCarte Romanze, 2014
Nel contributo si propone una nuova datazione per il Roi de Sicile di Adam de la Halle, opera nella quale il poeta celebra il re di Sicilia Carlo d’Angiò.
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doaj   +1 more source

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