Results 101 to 110 of about 966,720 (305)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Religions, 2017 Individual and romantic partner religiosity are positively associated with marital quality. However, many studies focus on married couples, rather than examining dating relationships, and rely on single-item measures of religiosity. More importantly, few
Michael Langlais, Siera Schwanz
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Paleontology: Outrunning Time [PDF]
, 2017 In this paper, I discuss several temporal aspects of paleontology from a philosophical perspective. I begin by presenting the general problem of “taming” deep time to make it comprehensible at a human scale, starting with the ...
Huss, John
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Il «Roi de Sicile» di Adam de la Halle: una nuova proposta di datazione e localizzazione
Carte Romanze, 2014 Nel contributo si propone una nuova datazione per il Roi de Sicile di Adam de la Halle, opera nella quale il poeta celebra il re di Sicilia Carlo d’Angiò.
Cesare Mascitelli
doaj +1 more source
Prevention in Middle School Matters: A Summary of Findings on Teen Dating Violence Behaviors and Associated Risk Factors Among 7th-Grade Students [PDF]
, 2012 Outlines baseline findings on dating; psychological, physical, and electronic abuse; and associated factors among seventh-graders. Calls for prevention efforts in middle school.
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source