Results 81 to 90 of about 1,791,338 (312)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Social SciencesThe present study investigates the roles of online dating violence and emotional dependence within the context of interpersonal relationships. The primary objective of this research is to analyze the perpetration and victimization of online dating ...
Mayra Castillo-Gonzáles +1 more
doaj +1 more source
A Page of the Poetic Dialogue Between S.A. Yesenin and N.A. Klyuev: About the Dating of the Poem “Beloved Land! My Heart Dreams of...” [PDF]
Литературный фактThe article consistently examines the stages of the creative history of S.A. Yesenin’s poem “Beloved Land! My Heart Dreams of...”. For the first time, we reproduce a facsimile of the autograph of the first version of the work (from the album of the ...
Svetlana A. Seregina, Sergey I. Subbotin
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Attached to dating apps: Attachment orientations and preferences for dating apps
Mobile Media & Communication, 2018 Our study examines attachment-related differences in the use of dating applications (dating apps). We collected online survey data regarding people’s attachment orientation and dating app preferences.
Kristi Chin +2 more
semanticscholar +1 more source
Religions, 2017 Individual and romantic partner religiosity are positively associated with marital quality. However, many studies focus on married couples, rather than examining dating relationships, and rely on single-item measures of religiosity. More importantly, few
Michael Langlais, Siera Schwanz
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Scalable relaxed clock phylogenetic dating
, 2017 Molecular clock models relate observed genetic diversity to calendar time, enabling estimation of times of common ancestry. Many large datasets of fast-evolving viruses are not well fitted by molecular clock models that assume a constant substitution rate
E. Volz, S. Frost
semanticscholar +1 more source
A Total-Evidence Approach to Dating with Fossils, Applied to the Early Radiation of the Hymenoptera
Systematic Biology, 2012 Phylogenies are usually dated by calibrating interior nodes against the fossil record. This relies on indirect methods that, in the worst case, misrepresent the fossil information. Here, we contrast such node dating with an approach that includes fossils
F. Ronquist +5 more
semanticscholar +1 more source