Results 61 to 70 of about 1,791,338 (312)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dating gone mobile: Demographic and personality-based correlates of using smartphone-based dating applications among emerging adults

New Media & Society, 2018
Mobile dating is more common with an increasing number of smartphone applications coming to market that aim to facilitate dating. In the current study, we investigated how dating app use and motivations related to demographic identity variables (i.e ...
S. Sumter, Laura Vandenbosch
semanticscholar   +1 more source

The fallout from Fukushima Daiichi nuclear accident profiles a new dating reference in ice and comparison with the Chernobyl accident

Environmental Research Letters, 2020
Absolute-age dating horizons play a pillar role in the reconstruction of an ice core chronology. In the modern era, these have included the global fallout from massive volcanic eruptions, atmospheric and marine thermonuclear weapons testing and nuclear ...
Feiteng Wang, Jing Ming, Ross Edwards, Zhongqin Li, Ninglian Wang   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

From first email to first date: Strategies for initiating relationships in online dating

Journal of Social and Personal Relationships, 2019
The present study explores the relationship initiation process in online dating using participants’ (N = 105) naturally occurring email messages to a prospective romantic partner.
L. Sharabi, T. Dykstra-DeVette
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

KUR’AN SÛRELERİNİN BÜTÜNLÜĞÜ VE TARİHLENDİRİLMESİ SORUNU ÜZERİNE BİR DEĞERLENDİRME

İslami İlimler Dergisi
Kur’an’ın, belirli bir tarih aralığında vuku bulan birtakım hadiselerle ilişkili olarak şifâhî bir formda inzal edildiği bilinmektedir. Hz. Peygamber’in Kur’an’ın ilk muhataplarına canlı bir diyalog niteliğinde ilettiği vahiy bölümlerinin halifeler ...
Orhan Güvel
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source