Results 71 to 80 of about 208,010 (304)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Sexual Double Standard, Dating Violence Recognition, and Sexual Assertiveness among University Students in South Korea

open access: yesAsian Nursing Research, 2019
Purpose: This study aimed to examine the association among sexual double standard, dating violence recognition, and sexual assertiveness among Korean university students.
Yujeong Kim, Eunmi Lee, Haeyoung Lee
doaj   +1 more source

Kekerasan dalam Pacaran dan Kecemasan Remaja Putri di Kabupaten Purworejo [PDF]

open access: yes, 2012
Background: Gender-based violence in Indonesia is that many cases occur. Since 1998,violence in dating the Rifka Annisa Women's Crisis Center is a case of the second largest afterthe violence against wives.
Ayu, S. M. (Suci)   +2 more
core  

Prevalence of Dating Partner Violence and Suicidal Ideation Among Male and Female University Students Worldwide [PDF]

open access: yes, 2008
This paper presents findings from the International Dating Violence study regarding the prevalence of physical assault, sexual coercion, and suicidal ideation among university students and explores the relationships between suicidal ideation and dating ...
Abbott   +35 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

PREVALENCE OF DATING VIOLENCE IN A SAMPLE OF MEXICAN ADOLESCENT MALES

open access: yesRevista de Psicología y Ciencias del Comportamiento de la Unidad Académica de Ciencias Jurídicas y Sociales, 2018
Some recent studies on dating violence have suggested that both sexes can be aggressors or recipients of violence. Therefore, this research explores the frequency with which 295 males, aged between 15 and 18, exercise and suffer violence in their dating ...
Gloria Zamora-Damián   +3 more
doaj   +1 more source

America Davila - Breaking the Cycle: An Examination of Environmental, Cognitive, and Emotional Factors of Intimate Partner Violence Victimization in Adolescence [PDF]

open access: yes, 2014
Recently, intimate partner violence (IPV) has gained considerable attention as a significant social and public health problem affecting not only adults but also adolescents. Based on Bandura’s social learning theory, considerable research has supported a
Davila, America
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Breaking the Cycle: An Examination of Environmental, Cognitive, and Emotional Factors of Intimate Partner Violence Victim [PDF]

open access: yes, 2016
Recently, intimate partner violence (IPV) has gained considerable attention as a significant social and public health problem affecting not only adults but also adolescents. Based on Bandura’s social learning theory, considerable research has supported a
Davila, America
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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