Results 141 to 150 of about 13,448,515 (313)
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
A qualitative exploration of patient experiences living with autoimmune encephalitis
Scientific ReportsAutoimmune encephalitis (AE) can result in significant long-term sequelae including cognitive dysfunction, leading to a reduction in quality of life. While cohort studies have highlighted these difficulties broadly, we require a deeper understanding of ...
Robb Wesselingh +10 more
doaj +1 more source
An evaluation of palliative care education in the specialist training programme in family medicine [PDF]
, 2010 Aim: The study aimed to evaluate the teaching in palliative care (PC) provided during the Specialist Training Programme in Family Medicine (STPFM) in Malta.
Mallia, Pierre, Abela, Jurgen C.
core
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Price Indexes for Medical Care Goods and Services: An Overview of Measurement Issues [PDF]
We review in considerable detail the conceptual and measurement issues that underlie construction of medical care price indexes in the U.S., particularly the medical care consumer price indexes (MCPIs) and medical-related producer price indexes (MPPIs ...
Zvi Griliches +4 more
core
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
FEBS Open Bio, EarlyView.In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
The Medical Day Care (MDC) Services Waiver provides health, social, and related support services in a community based setting to functionally disabled adults aged 16 and older.
The Hilltop Institute
core +1 more source
[The role of the general physician in present-day medical care in Mexico].
Gaceta medica de Mexico, 2005 The issue of how medical specialization does not represent a novelty is discussed. The authors also approach the question of how the advantages and shortcomings of medical care provided by both general practitioners and medical specialists have been equally addressed previously by the ancient Greek classics as well as by outstanding Mexican specialists
José, Narro-Robles +1 more
openaire +1 more source
A nationwide student survey on biochemistry learning resources in Italy
FEBS Open Bio, EarlyView.We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti +4 more
wiley +1 more source
Establishing monthly cardiac arrest simulation in the Regional Day Procedure Centre
BJA OpenJ.T. Kennedy +6 more
doaj +1 more source