Results 121 to 130 of about 156,448 (285)

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

An assessment of the load modifying potential of model predictive controlled dynamic facades within the California context [PDF]

, 2020
California is making major strides towards meeting its greenhouse gas emission reduction goals with the transformation of its electrical grid to accommodate renewable generation, aggressive promotion of building energy efficiency, and increased emphasis ...
Blum, DH, Gehbauer, C, Lee, ES, Wang, T
core  

Studies of Daylight Factor: Improving Daylight Factor by the use of Net Curtains

, 1998
An examination of the effect of various types of net curtain on the daylight factor in a domestic room of 4.8m in depth. The types of fabric tested are all commonly in use in the United Kingdom to provide privacy to windows: polyester net, muslin cotton and patterned polyester lace.
Anderson, Jane, Thompson, Michael
openaire  

Hot Electron‐Assisted Noble‐Metal‐Free Synergistic Photothermal Catalyst for Solar‐Driven Wastewater Remediation and Microbial Disinfection

Advanced Science, EarlyView.
A multifunctional Bi2Te3@CdS hybrid system is presented for solar‐driven wastewater remediation and indoor disinfection. The catalyst coated on PU foam efficiently harvests visible‐NIR light to generate heat and reactive oxygen species, enabling the rapid mineralization of organic pollutants.
Manish Kumar Sharma, Bishal Kumar Nahak, Parag Parashar, Uday Kumar Singh, Arshad Khan, Jaba Roy Chowdhury, Parthasarathi Pal, Dongwhi Choi, Hae Gyun Lim, Yu‐Lun Chueh, Zong‐Hong Lin   +10 more
wiley   +1 more source

Assessment of the discrepancy between daylight factor and using illuminance data methods by climate zones under EN:17037

Advances in Civil and Architectural Engineering
Conducting a rigorous evaluation of the daylight performance of buildings is essential for human health and energy efficiency. Today, there are two main methods used for analysis: the daylight factor, which has been used since the early 1900s, and the ...
Gülçin Gülsüm Konuk Taştan, Işıl İplik, Şensin Yağmur, Hızır Gökhan Uyduran   +3 more
doaj   +1 more source

Investigating Daylight Quality In Malaysian Government Office Buildings Through Daylight Factor And Surface Luminance

, 2011
In recent years, there has been an increasing interest in using daylight to save energy in buildings. In tropical regions, daylighting is always an energy saver. On the other hand, daylight provides visual comfort. According to standards, it shows that many criteria should be taken into consideration in order to have daylight utilization and visual ...
Mohd Zin Kandar, Mohd Sabere Sulaiman, Rashid, Yong Razidah, Dilshan Remaz Ossen, Aminatuzuhariah MAbdullah, Wah, Lim Yaik, Nikpour, Mansour   +6 more
openaire   +1 more source

Ultrasonic‐Assisted Photocatalytic Conversion of Air to Nitric Acid Under Ambient Conditions

Advanced Science, EarlyView.
Ultrasound‐assisted photocatalytic air oxidation to nitrate enhances soil nitrogen fertilizer dynamics, thereby enabling improved energy conversion efficiency and sustainable agriculture. ABSTRACT The production of nitric acid (HNO3) holds significant importance in the chemical industry, and achieving direct air‐to‐HNO3 conversion with high efficiency ...
Shiming Chen, Hanlan Hong, Yunchuan Tu, Chao Zhen, Rui Zheng, Yuxi Yao, Junxiong Chen, Tianlin Wang, Xiumei Zhan, Fanhe Kong, Huazhe Yang, Gang Liu   +11 more
wiley   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

Advanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin, Jiale Sun, Yuqing Mao, Yuhao Tang, Fuan Wang, Zhihong Liu, Jing Wang   +6 more
wiley   +1 more source

Local‐to‐Nonlocal Second‐Harmonic Generation from Electrically Tunable Intersubband Polaritonic Metasurfaces

Advanced Science, EarlyView.
A local‐to‐nonlocal SHG process is demonstrated on an electrically tunable metasurface, combining an LSPR at the FF with a TM‐GMR at the SH to achieve independent dual tunability. Through modal‐overlap engineering of the proposed scheme, a high‐χ(2) MQW meta‐atom delivers strong nonlinearity while achieving 2‐DoF SH control with minimal trade‐offs ...
Jaesung Kim, Hyeongju Chung, Seongjin Lee, Gerhard Boehm, Mikhail A. Belkin, Jongwon Lee   +5 more
wiley   +1 more source