Results 141 to 150 of about 156,325 (301)

Effect of Laser Posterior Nasal Neurolysis for the Treatment of Chronic Rhinitis: A Randomized Controlled Trial

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background To determine the safety and efficacy of laser ablation of the posterior nasal nerve (PNN) for the treatment of chronic rhinitis. Methods This study was a single‐center, prospective, single‐blinded, randomized sham‐controlled trial. Patients with a 24‐h reflective Total Nasal Symptom Score (rTNSS) ≧ 5, rhinorrhea ≧ 2, and congestion ≧
Jyun‐Yi Liao   +9 more
wiley   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

open access: yesAnnals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa   +6 more
wiley   +1 more source

Daily‐Life, Sensor‐Derived Tremor Measures Are Sensitive to Progression in Early Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Sensitive outcome measures are critical for evaluating the efficacy of novel treatments for Parkinson's disease (PD). In this study, we assess the sensitivity to change of sensor‐derived daily‐life tremor measures over 2 years in unmedicated and medicated persons with early PD.
Nienke A. Timmermans   +10 more
wiley   +1 more source

A Dithio Vinylthio C2 Synthon Enabling Crystalline and Luminescent Sulfur‐Decorated Polymers

open access: yesAngewandte Chemie International Edition, EarlyView.
Transforming CaC2 into a modular C2 building block enables the synthesis of α,ω‐bis(vinylthio) monomer and its conversion into crystalline, sequence‐defined sulfur‐decorated polymers. Their dense thioether clustering induces nonconventional luminescence and provides structure–function control in a more‐sustainable polymer platform.
Bercis Pektas   +4 more
wiley   +1 more source

Design and Optimization of a Novel Kalina‐Organic Rankine Cycle System Based on LNG Cold Energy Utilization

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study proposes a novel integrated system (SDKC‐DORC) that combines a split‐flow dual‐pressure Kalina cycle with a secondary organic Rankine cycle for the synergistic utilization of solar energy and liquefied natural gas (LNG) cold energy.
Ke Xiao   +6 more
wiley   +1 more source

Real‐time monitoring of root dielectric properties for assessing crop plant damage caused by foliar application of glyphosate

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise There is a knowledge gap regarding how foliar injury and restricted water uptake can be detected by measuring root dielectric response. This pot study nondestructively evaluated the efficiency of real‐time dielectric measurement to monitor the effects of glyphosate spraying.
Imre Cseresnyés   +2 more
wiley   +1 more source

Light‐Responsive Carbon Dots with Photochromism and Excitation‐Dependent Room Temperature Phosphorescence

open access: yesAdvanced Physics Research, EarlyView.
A light‐responsive system with photochromism and excitation‐dependent phosphorescence was constructed by microwave synthesis of nitrogen‐doped carbon dots(N‐CDs), which provides insights into the design and synthesis of CDs with multifunctional optical properties, promoting the application expansion of intelligent responsive materials in the fields of ...
Xiaoqi Fang   +7 more
wiley   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu   +6 more
wiley   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel   +12 more
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

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