Results 151 to 160 of about 156,325 (301)

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

open access: yesBiological Reviews, EarlyView.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye   +4 more
wiley   +1 more source

A mosaic of microclimates: biodiversity outcomes and wildlife habitat potential in large‐scale solar facilities

open access: yesBiological Reviews, EarlyView.
ABSTRACT The rapid global expansion of photovoltaic (PV) solar facilities, now comprising nearly 80% of the recent and projected growth of renewable electricity, represents one of the most significant land‐use changes of the 21st century. While PV facilities are critical for decarbonising energy systems, their large spatial footprint and infrastructure
Tom Armstrong   +4 more
wiley   +1 more source

Configuration effects on satellite charging response [PDF]

open access: yes
The response of various spacecraft configurations to a charging environment in sunlight was studied using the NASA Charging Analyzer Program code. The configuration features geometry, type of stabilization, and overall size.
Purvis, C. K.
core   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

The Use of Renewable Energy in Prominent City Buildings: A Diffusion Study on Top European Football Organizations

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The present study applied the diffusion of innovation theory to investigate the rate of diffusion of renewable energy sources used by Europe's top professional football stadiums and the relationship with carbon neutrality. A discrete diffusion model estimated the diffusion of renewable energy to saturation, and a multivariate logistic ...
Chad S. Seifried   +2 more
wiley   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy   +3 more
wiley   +1 more source

Engineered Carbon Dots as Multifunctional Nanoplatforms for Next‐Generation High‐Performance Advanced Batteries

open access: yesCarbon Energy, EarlyView.
Herein, we mainly summarize the characteristics of the main types of carbon dots (CDs), analyze the strategies for improving advanced batteries' performance via incorporating CDs, comprehensively summarize recent applications of CDs in the main components (electrode, electrolyte, and separator) of advanced batteries, and propose the technical ...
Chuang Jiang   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy