Results 31 to 40 of about 86,985 (257)

Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo

Neurobiology of Disease, 2020
Amyotrophic Lateral Sclerosis (ALS), a late-onset neurodegenerative disorder characterized by the loss of motor neurons in the central nervous system, has no known cure to-date.
Neha Gogia, Ankita Sarkar, Abijeet Singh Mehta, Ph.D., Nandini Ramesh, Prajakta Deshpande, Madhuri Kango-Singh, Udai Bhan Pandey, Amit Singh   +7 more
doaj   +1 more source

Chiral Phase Change Nanomaterials

Advanced Functional Materials, EarlyView.
This work demonstrates reversible, non‐volatile phase transitions in chiral Ge2${\rm Ge}_2$Sb2${\rm Sb}_2$Te5${\rm Te}_5$ (GST) nanohelices for high‐speed optical modulation of chirality and dynamic control of the state of polarization (SOP). The chiral nanostructures are fabricated using a highly directional, wafer‐scale physical vapor deposition ...
Joshua A. Burrow, Md Shah Alam, Riad Yahiaoui, Evan M. Smith, Ryan Laing, Jules Gardener, Thomas A. Searles, Piyush J. Shah, Shivashankar Vangala, Joshua R. Hendrickson, Andrew M. Sarangan, Imad Agha   +11 more
wiley   +1 more source

Photonic Time Crystals and Time‐Varying Electromagnetic Metamatter: A New Direction for Ultrafast Tunable Photonic and Microwave Materials and Devices

Advanced Science, EarlyView.
Photonic time crystals (PTCs) are systems in which electromagnetic parameters are modulated periodically in time, producing momentum bandgaps via temporal scattering rather than spatial Bragg processes. This review examines the theoretical frameworks, modeling, and computational tools for time‐varying media, and summarizes experimental demonstrations ...
Ranjan Kumar Patel, Shriram Ramanathan, Ronald P. Jenkins, Michael J. Carter   +3 more
wiley   +1 more source

Protocol to study cell death using TUNEL assay in Drosophila imaginal discs

STAR Protocols, 2022
Summary: Cell death maintains tissue homeostasis by eliminating dispensable cells. Misregulation of cell death is seen in diseases like cancer, neurodegeneration, etc.
Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Abijeet Singh Mehta, Amit Singh   +3 more
doaj   +1 more source

Differences in predominant collagen fiber orientation between dorsal and plantar trabecular bone tracts of adult mule deer calcanei suggest strain‐mode‐specific adaptation

The Anatomical Record, EarlyView.
Polarized microscopic images of the outer bone cortex (a and b) and deeper trabecular bone (c and d) of the deer calcaneus in thin cross‐sections. The brighter gray levels reflect more oblique‐to‐transverse collagen fibers in the compression/dorsal bone (a, c) and the darker gray levels reflect more longitudinal collagen in the tension/plantar bone (b,
John G. Skedros, John T. Cronin, Chad S. Mears, Brett W. Richards   +3 more
wiley   +1 more source

A novel bubbling fluid bed reactor for the autothermal pyrolysis of waste plastics

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract A new pilot‐scale fluidized bed reactor operated under continuous conditions was developed and tested for the thermal pyrolysis of high‐density polyethylene (HDPE). The study focused on assessing the reliability and operability of the system under different operating conditions (400–550°C), while monitoring mass and energy balances, product ...
Khadija Olivia Ogoula Igouwe, Tchini Sévérin Tanoh, Jasmin Blanchard, Inès Esma Achouri, Nicolas Abatzoglou   +4 more
wiley   +1 more source

Acoustic‐driven surface cleaning with millimeter‐sized bubbles at translational resonance

Droplet, EarlyView.
Time‐lapse visualization comparing bubble trajectories. The top panel (0 Hz) shows a bubble's linear path under no acoustic forcing, while the bottom panel (50 Hz) demonstrates the oscillatory motion induced by acoustic waves at a resonance mode. This mechanism holds promising potential for applications such as surface cleaning.
Yan Jun Lin, Zhengyang Liu, Sunghwan Jung   +2 more
wiley   +1 more source

Current understanding and distinct features of multifocal and multicentric breast cancers

Cancer Reports, 2023
Background Multifocal (MF) and multicentric (MC) breast cancers are referred to as synchronous, multiple ipsilateral breast cancers; however, the definitions vary among the literature, which has made understanding and analyzing these diseases challenging.
Elizabeth Avera, Lilia Valentic, Loan Bui   +2 more
doaj   +1 more source

Ketogenic diet therapy for children with super‐refractory status epilepticus in intensive care: International clinical practice recommendations

Epilepsia Open, EarlyView.
Abstract Objective We aimed to create practical recommendations to support healthcare teams starting ketogenic diet therapy (KDT) for children with super‐refractory status epilepticus in intensive care settings. Methods A literature review was conducted to extract published data on patient selection, diet prescription, diet initiation, monitoring, fine‐
Robyn Blackford, Victoria J. Whiteley, Isobel Hardy, Marisa Armeno, Tessa Bollard, J. Helen Cross, Christin Eltze, Susan George, Charlotte Howard, A. Laura Nijstad, Erin Talzzia, Chris Paget, Samiran Ray, Zoe Simpson, Elizabeth Song‐Pozderac, Agnieszka Szmurlo, Charlene Tan‐Smith, Lisa Vanatta, Elles van der Louw, Natasha E. Schoeler, on behalf of the Ketogenic Dietitians Research Network   +20 more
wiley   +1 more source

Gene Regulatory Network Homoplasy Underlies Recurrent Sexually Dimorphic Fruit Fly Pigmentation

Frontiers in Ecology and Evolution, 2020
Traits that appear discontinuously along phylogenies may be explained by independent origins (homoplasy) or repeated loss (homology). While discriminating between these models is difficult, the dissection of gene regulatory networks (GRNs) which drive ...
Jesse T. Hughes, Melissa E. Williams, Rachel Johnson, Sumant Grover, Mark Rebeiz, Thomas M. Williams, Thomas M. Williams   +6 more
doaj   +1 more source