Results 21 to 30 of about 40,050 (263)

The Contribution of Anterior Segment Abnormalities to Changes in Intraocular Pressure in the DBA/2J Mouse Model of Glaucoma: DBA/2J-Gpnmb+/SjJ Mice as Critical Controls

Frontiers in Neuroscience, 2022
The contributions of anterior segment abnormalities to the development of ocular hypertension was determined in the DBA/2J mouse model of glaucoma. Intraocular pressure (IOP) was measured non-invasively.
Landon J. Rohowetz, Marc E. Mardelli, R. Scott Duncan, Sean M. Riordan, Peter Koulen, Peter Koulen   +5 more
doaj   +1 more source

Effect of Four Novel Bio-Based DES (Deep Eutectic Solvents) on Hardwood Fractionation

Molecules, 2020
Using the basic principle of construction between a hydrogen bond acceptor (HBA) and a hydrogen bond donor (HBD), four bio-based deep eutectic solvents (DESs) were prepared in a 1:2 molar ratio of HBA:HBD. 2,3-Dihydroxypropyl-1-triethylammonium chloride (
Paulo Torres, Mercè Balcells, Enrique Cequier, Ramon Canela-Garayoa   +3 more
doaj   +1 more source

OpenMedLM: prompt engineering can out-perform fine-tuning in medical question-answering with open-source large language models

Scientific Reports
LLMs can accomplish specialized medical knowledge tasks, however, equitable access is hindered by the extensive fine-tuning, specialized medical data requirement, and limited access to proprietary models.
Jenish Maharjan, Anurag Garikipati, Navan Preet Singh, Leo Cyrus, Mayank Sharma, Madalina Ciobanu, Gina Barnes, Rahul Thapa, Qingqing Mao, Ritankar Das   +9 more
doaj   +1 more source

Best practices in doctoral retention: Mentoring

Higher Learning Research Communications, 2014
The aim of this critical literature review is to outline best practices in doctoral retention and the successful approach of one university to improve graduation success by providing effective mentorship for faculty and students alike.
Judie L. Brill, Karen K. Balcanoff, Denise Land, Maurice Gogarty, Freda Turner   +4 more
doaj   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Early life gut microbiome and its impact on childhood health and chronic conditions

Gut Microbes
The development of the gut microbiome is crucial to human health, particularly during the first three years of life. Given its role in immune development, disturbances in the establishment process of the gut microbiome may have long term consequences ...
Harold Nunez, Pamela A. Nieto, Ruben A. Mars, Maryam Ghavami, Cheryl Sew Hoy, Kimberley Sukhum   +5 more
doaj   +1 more source

Bioinspired Mechanically Robust Organic–Inorganic Hybridized Bio‐Adhesives With up to 50% Inorganic Components by Bi‐Continuous Phase Engineering

Advanced Functional Materials, EarlyView.
A robust plant protein adhesive was prepared by fabricating a bi‐continuous organic–inorganic hybrid structure. Compared with traditional organic–inorganic hybrid adhesives, the addition amount of inorganic phase is increased from 0.2%–3.0% to 50%, and the strength and toughness are increased by 6 and 121 times, respectively.
Zheng Liu, Wenlong Luo, Xu Yang, Xin Zhang, Yuru Zhu, Jingchao Li, Jianzhang Li, Jing Luo, Zhezhe Zhou, Pingan Song, Qiang Gao   +10 more
wiley   +1 more source

Dual Acidic pH‐Responsive Post‐Crosslinked E‐Spun Nanofibrous Scaffolds Exhibiting Enhanced Disassembly and Release for Localized Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Dual acidic pH‐responsive degradable e‐spun nanofibrous mats crosslinked with acid‐labile imine and boronic ester linkages that exhibit rapid degradation and enhanced release of encapsulated anticancer drugs through their acid‐catalyzed hydrolysis and their doxorubicin‐loaded mats having desired antitumoral activity and hemocompatibility, as promising ...
Sofia Nieves Casillas‐Popova, Arianna Cirillo, Cameron D. Skinner, Dajana Vuckovic, Jung Kwon Oh   +4 more
wiley   +1 more source

Barrier‐forming, drug‐free nasal spray reduces allergic symptoms induced by house dust mite allergen

Clinical and Translational Allergy, 2023
Background House Dust Mite (HDM) is the most common indoor allergen triggering allergic symptoms. First‐line pharmacotherapy treatment is recommended in international guidelines, while the avoidance of allergens represents a still unmet guideline ...
Patricia Couroux, Nicole Grosse, Anne Marie Salapatek, Yasmeen Goyal, Oliver Pfaar, Ilja P. Hohenfeld   +5 more
doaj   +1 more source

Aqueous humor phospholipids of DBA/2J and DBA/2J-Gpnmb+/SjJ mice [PDF]

Biochimie, 2015
To compare phospholipid profiles [phosphatidylcholine (PC), phosphatidylserine (PS), phosphatidylethanolamine (PE), and phosphatidylinositol (PI)] of normotensive and hypertensive aqueous humor (AH) from DBA/2J and compare them with phospholipid profiles of DBA/2J-Gpnmb(+)/SjJ mice.AH was obtained from young-normotensive DBA/2J, old -hypertensive DBA ...
Haiyan, Wang, Genea, Edwards, Catalina, Garzon, Carmen, Piqueras, Sanjoy K, Bhattacharya   +4 more
openaire   +2 more sources