Results 31 to 40 of about 72,755 (280)

DBA/2J Genetic Background Exacerbates Spontaneous Lethal Seizures but Lessens Amyloid Deposition in a Mouse Model of Alzheimer’s Disease

PLoS ONE, 2015
Alzheimer’s disease (AD) is a leading cause of dementia in the elderly and is characterized by amyloid plaques, neurofibrillary tangles (NFTs) and neuronal dysfunction.
Harriet M Jackson, Kristen D. Onos, Keating W. Pepper, Leah C. Graham, E. Akeson, Candice Byers, L. Reinholdt, W. Frankel, G. Howell   +8 more
semanticscholar   +1 more source

Early life gut microbiome and its impact on childhood health and chronic conditions

Gut Microbes
The development of the gut microbiome is crucial to human health, particularly during the first three years of life. Given its role in immune development, disturbances in the establishment process of the gut microbiome may have long term consequences ...
Harold Nunez, Pamela A. Nieto, Ruben A. Mars, Maryam Ghavami, Cheryl Sew Hoy, Kimberley Sukhum   +5 more
doaj   +1 more source

Best practices in doctoral retention: Mentoring

Higher Learning Research Communications, 2014
The aim of this critical literature review is to outline best practices in doctoral retention and the successful approach of one university to improve graduation success by providing effective mentorship for faculty and students alike.
Judie L. Brill, Karen K. Balcanoff, Denise Land, Maurice Gogarty, Freda Turner   +4 more
doaj   +1 more source

Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma

Frontiers in Neuroscience, 2014
Axonal transport deficits have been reported as an early pathology in several neurodegenerative disorders, including glaucoma. However, the progression and mechanisms of these deficits are poorly understood.
C. Dengler-Crish, Matthew A. Smith, D. Inman, G. Wilson, J. Young, Samuel Crish   +5 more
semanticscholar   +1 more source

OpenMedLM: prompt engineering can out-perform fine-tuning in medical question-answering with open-source large language models

Scientific Reports
LLMs can accomplish specialized medical knowledge tasks, however, equitable access is hindered by the extensive fine-tuning, specialized medical data requirement, and limited access to proprietary models.
Jenish Maharjan, Anurag Garikipati, Navan Preet Singh, Leo Cyrus, Mayank Sharma, Madalina Ciobanu, Gina Barnes, Rahul Thapa, Qingqing Mao, Ritankar Das   +9 more
doaj   +1 more source

Barrier‐forming, drug‐free nasal spray reduces allergic symptoms induced by house dust mite allergen

Clinical and Translational Allergy, 2023
Background House Dust Mite (HDM) is the most common indoor allergen triggering allergic symptoms. First‐line pharmacotherapy treatment is recommended in international guidelines, while the avoidance of allergens represents a still unmet guideline ...
Patricia Couroux, Nicole Grosse, Anne Marie Salapatek, Yasmeen Goyal, Oliver Pfaar, Ilja P. Hohenfeld   +5 more
doaj   +1 more source

Effects of Molecular Designs and Double‐Network Morphologies for Bioadhesive Semiconductors

Advanced Functional Materials, EarlyView.
This study establishes molecular‐to‐mesoscale design rules for bioadhesive semiconducting polymers (BASCs). It identifies how side‐chain length, double‐network formation, and film thickness modulate adhesion strength and electronic performance, providing insight into the rational design of intrinsically adhesive semiconductors for stable and efficient ...
Zhichang Liu, Nan Li, Yuqing Chen, Naisong Shan, Shinya Wai, Jie‐Hao Chen, Aidan Ziaja, Shrayesh N. Patel, Sihong Wang   +8 more
wiley   +1 more source

Bandwidth Allocation DBA (BA-DBA) Algorithm for xPON Networks

International Journal of Computer Applications, 2012
Optical Networks (PONs) technology is considered as a promising solution for the next-generation broadband access network. In this paper we present different dynamic bandwidth algorithms (DBA) and estimate the bandwidth between OLT and ONT in order to improve network efficiency and packet processing.
Al-Arfaj Khalid, Karamitsos Ioannis
openaire   +1 more source

Crystal Engineering of Reticular Materials for Gas‐ and Liquid‐Phase Hydrocarbon Separation

Advanced Materials, EarlyView.
Crystal engineering enables systematic study of structure/function relationships as exemplified by pore engineering of reticular sorbents, including porous coordination networks and covalent organic frameworks. This review assesses such studies applied across the full scope of industrially relevant hydrocarbon separations to provide insight into how ...
Xia Li, Soumya Mukherjee, Michael J. Zaworotko   +2 more
wiley   +1 more source

LLM As DBA

, 2023
Database administrators (DBAs) play a crucial role in managing, maintaining and optimizing a database system to ensure data availability, performance, and reliability. However, it is hard and tedious for DBAs to manage a large number of database instances (e.g., millions of instances on the cloud databases).
Zhou, Xuanhe, Li, Guoliang, Liu, Zhiyuan
openaire   +3 more sources