Results 21 to 30 of about 125,770 (300)
Brain Sciences, 2016 Obesity is a chronic, progressive and prevalent disorder. Morbid obesity, in particular, is associated with numerous comorbidities and early mortality. In patients with morbid obesity, pharmacological and behavioral approaches often have limited results. Bariatric surgery is quite effective but is associated with operative failures and a non-negligible
Ruth Franco +7 more
openaire +3 more sources
Neurobehavioral deficits in db/db diabetic mice [PDF]
Physiology & Behavior, 2010 Recent clinical studies indicate neurobehavioral disturbances in type-2 diabetics. However, there is paucity of preclinical research to support this concept. The validity of db/db mouse as an animal model to study type-2 diabetes and related complications is known.
Sharma, Ajaykumar Narayan +3 more
openaire +4 more sources
Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]
, 2015 Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul +9 more
core +3 more sources
Why dried blood spots are an ideal tool for CYP1A2 phenotyping [PDF]
, 2014 Background and Objective: Dried blood spot (DBS) sampling has gained wide interest in bioanalysis during the last decade and has already been successfully applied in pharmacokinetic and phenotyping studies.
De Kesel, Pieter +2 more
core +2 more sources
Skeletal Muscle Pathogenesis in Polyglutamine Diseases
Cells, 2022 Polyglutamine diseases are characterized by selective dysfunction and degeneration of specific types of neurons in the central nervous system. In addition, nonneuronal cells can also be affected as a consequence of primary degeneration or due to neuronal
Caterina Marchioretti +5 more
doaj +1 more source
Decision by sampling: the role of the decision environment in risky choice [PDF]
, 2009 Decision by sampling (DbS) is a theory about how our environment shapes the decisions that we make. Here, I review the application of DbS to risky decision making.
Stewart, Neil
core +1 more source
Is Deep Brain Stimulation a viable treatment for substance-related addiction? [PDF]
Romanian Journal of Neurology, 2019 For the ability to modulate the activity of dysregulated networks Deep Brain Stimulation (DBS) of areas involved in reward system and motivational states may have a potential application in addiction despite risks associated with its invasiveness.
Giusy Guzzi +3 more
doaj +1 more source
Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home : an exploratory study [PDF]
, 2013 Background: Gamma-hydroxybutyric acid (GHB), well known as a party drug, especially in Europe, is also legally used (sodium oxybate, Xyrem (R)) to treat a rare sleep disorder, narcolepsy with cataplexy.
Hertegonne, Katrien +3 more
core +1 more source
The Pan African Medical Journal, 2015 INTRODUCTION: l'infection au VIH chez les nouveau-nés par leur mère peut être réduite grâce à des programmes de prévention de transmission mère-enfant du VIH (PTME). L'objectif dans cette étude était d'évaluer le traitement antirétroviral chez les femmes
Serge Theophile Soubeiga +12 more
doaj +1 more source
Brain Sciences, 2019 Weight changes are insufficiently understood adverse events of deep brain stimulation. In this context, exploring neural networks of weight control may inform novel treatment strategies for weight-related disorders.
Juan Carlos Baldermann +7 more
doaj +1 more source