Results 101 to 110 of about 27,025 (207)
Conformational dynamics in insulin receptor kinase reveal a type III allosteric pocket
Abstract Allosteric modulation is a promising strategy for selective kinase inhibition, yet structural insights into allosteric pockets remain limited across the human kinome. In this work, we present comprehensive characterization of a type III allosteric pocket in the insulin receptor kinase (IRK), integrating structural, conformational, and ...
Jyoti Verma, Harish Vashisth
wiley +1 more source
ABSTRACT Expansins loosen plant cell wall networks through disrupting non‐covalent bonds between cellulose microfibrils and matrix polysaccharides. Whereas expansins were first discovered in plants, expansin‐related proteins have since been identified in bacteria and fungi.
Anna Pohto +8 more
wiley +1 more source
DBSCAN in Domains with Periodic Boundary Conditions
Many scientific problems involve data that is embedded in a space with periodic boundary conditions. For instance, this can be related to an inherent cyclic or rotational symmetry in the data or a spatially extended periodicity. When analyzing such data,
Xander M. de Wit, Alessandro Gabbana
doaj +1 more source
Flow History Effects on River Bifurcation Dynamics in a Himalayan River
Abstract Dynamic gravel bed rivers experience frequent changes in channel position and flow distribution between branches, which can alter the location and extent of flooding. Changes in flow routing can significantly impact livelihoods, habitats and infrastructure in adjacent floodplains. Here, we test whether variations in seasonal discharge patterns
C. Cload +3 more
wiley +1 more source
GO-DBSCAN: Improvements of DBSCAN Algorithm Based on Grid [PDF]
Ling Feng +3 more
openaire +1 more source
Distinct Cloud‐to‐Ground Lightning Properties in Frontal Versus Warm‐Sector Heavy Rainfall Events
Abstract Do systematic differences in cloud‐to‐ground (CG) lightning properties—particularly return stroke number and current intensity—exist across different thunderstorm types? This question is foundational not only to the atmospheric electricity but also to advancing lightning risk prediction, which crucially depends on a robust understanding of how
Xiaotian Wu +6 more
wiley +1 more source
Stunting, a condition where children are malnourished for a long period, causes growth failure in children. West Java, Central Java, and East Java are the 3 provinces with the highest prevalence of stunting in 2021.
Bagus Sumargo +9 more
doaj +1 more source
Abstract Volcano deformation measured through Interferometric Synthetic Aperture Radar (InSAR) is ideal for volcano monitoring in many regions due to its global coverage, characteristic spatio‐temporal patterns, and modeling insights. Routinely acquired and processed Sentinel‐1 InSAR datacubes provide the first opportunity to systematically catalog ...
B. Ireland +4 more
wiley +1 more source
Impact‐Based Drought Detection via Interpretable Machine Learning and Causal Discovery
Abstract The intensification of drought events due to climate change presents unprecedented risks and widespread socioenvironmental impacts. Traditional drought indices, which rely on hydrometeorological anomalies, often fall short in capturing the full extent of these impacts, as they primarily focus on isolated precursors (e.g., precipitation deficit
Paolo Bonetti +6 more
wiley +1 more source
Abstract Groundwater drought represents one of the most pervasive and difficult‐to‐monitor forms of water scarcity, threatening the reliability of freshwater supply for over 2 billion people worldwide, agricultural productivity, and ecosystem health.
Parnian Ghaneei, Hamid Moradkhani
wiley +1 more source

