Results 61 to 70 of about 549,171 (289)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

A RISC-V Vector Processor With Simultaneous-Switching Switched-Capacitor DC-DC Converters in 28 nm FDSOI [PDF]

open access: yes, 2016
This work demonstrates a RISC-V vector microprocessor implemented in 28 nm FDSOI with fully integrated simultaneous-switching switched-capacitor DC-DC (SC DC-DC) converters and adaptive clocking that generates four on-chip voltages between 0.45 and 1 V ...
Alon, E   +18 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Efficient Voltage Regulation with Modified Hybrid SEPIC DC-DC-Converter

open access: yesMATEC Web of Conferences, 2018
Switch mode dc-dc converters are attractive for their small size, ease of control and efficient power conversion. Output voltage is regulated by duty cycle control of semiconductor switch of switch mode dc-dc converters.
Ali Azam Khan Md.   +1 more
doaj   +1 more source

Efficient LDO-Assisted DC/DC buck converter for integrated power management system [PDF]

open access: yes, 2016
DC-DC Switching Converters; Voltage Linear Regulators; Linear-Assisted DC-DC Voltage Regulators.Postprint (published ...
Martínez García, Herminio
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

A system efficiency improvement of DC fast-chargers in electric vehicle applications: Bypassing second-stage full-bridge DC-DC converter in high-voltage charging levels

open access: yesAin Shams Engineering Journal, 2023
In this paper, the DC fast charger module with its circuit topologies is studied detailed. The electric vehicle batteries are charged via DC fast chargers for quick charging.
Yusuf Yasa
doaj   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams   +14 more
wiley   +1 more source

Review and Selection Strategy for High-Accuracy Modeling of PWM Converters in DCM

open access: yesJournal of Electrical and Computer Engineering, 2018
Among various modeling methods for DC-DC converters introduced in the past two decades, the state-space averaging (SSA) and the circuit averaging (CA) are the most general and popular exhibiting high accuracy.
Yu-Jun Mao   +4 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

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